PAF C-18:1

PAF C-18:1 is a naturally occurring phospholipid produced by cells upon stimulation and plays a role in the establishment and maintenance of the inflammatory response. It is less potent than PAF C-16 (Cay-60900) and PAF C-18 (Cay-60910) in the induction of neutrophil chemotaxis, but is equipotent to PAF C-16 and PAF C-18 in promoting eosinophil migration. PAF C-18:1 activates the PAF receptor and has been used in antibody binding experiments to determine the importance of an acyl linkage at the sn-2 position for recognition at this receptor.Formal Name: 7R-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptacos-18Z-en-1-aminium, 4-oxide inner salt. CAS Number: 85966-90-1. Synonyms: 1-Oleoyl-2-acetyl-sn-glycero-3-phosphorylcholine, Platelet-activating Factor C-18:1. Molecular Formula: C28H56NO7P. Formula Weight: 549.7. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 10 mg/ml, PBS (pH 7.2): 20 mg/ml, Water: 20 mg/ml. SMILES: CC(O[C@@H](COP(OCC[N+](C)(C)C)([O-])=O)COCCCCCCCC/C=C\CCCCCCCC)=O. InChi Code: InChI=1S/C28H56NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-33-25-28(36-27(2)30)26-35-37(31,32)34-24-22-29(3,4)5/h13-14,28H,6-12,15-26H2,1-5H3/b14-13-/t28-/m1/s1. InChi Key: ZBOQHUSCQCEBGK-JLRCLJKCSA-N. Side Chain Carbon Sum: 20:1.