Norhyodeoxycholic Acid

Norhyodeoxycholic acid (NHDCA) is a synthetic bile acid and a derivative of hyodeoxycholic acid (HDCA, Cay-20294). NHDCA is an intermediate in the synthesis of 3beta-sulfooxy-7beta-hydroxy-24-nor-5-cholen-23-oic acid, which has been used as an internal standard for the quantification of Delta5-bile acid conjugates that have been identified in patients with Niemann-Pick disease type C1.Formal Name: (5beta)-3alpha,6alpha-dihydroxy-24-norcholan-23-oic acid. CAS Number: 77518-23-1. Synonyms: 3alpha,6alpha-Dihydroxy-24-nor-5beta-cholan-23-oic Acid, NHDCA. Molecular Formula: C23H38O4. Formula Weight: 378.6. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30mg/mL, DMF:PBS (pH 7.2) (1:1): 0.5mg/mL, DMSO: 20mg/mL, Ethanol: 20mg/mL. SMILES: C[C@H](CC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])C[C@H](O)[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C. InChi Code: InChI=1S/C23H38O4/c1-13(10-21(26)27)16-4-5-17-15-12-20(25)19-11-14(24)6-8-23(19,3)18(15)7-9-22(16,17)2/h13-20,24-25H,4-12H2,1-3H3,(H,26,27)/t13-,14-,15+,16-,17+,18+,19+,20+,22-,23-/m1/s1. InChi Key: ZBAVIUQLFUYWMT-NNUWNQTCSA-N.