Norbixin (hydrate)

Norbixin (hydrate)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay40132-1 1 mg -

6 - 10 business days*

204.00€
Cay40132-5 5 mg -

6 - 10 business days*

919.00€
 
Norbixin is a carotenoid that has been found in B. orellana and has diverse biological... more
Product information "Norbixin (hydrate)"
Norbixin is a carotenoid that has been found in B. orellana and has diverse biological activities. It binds to peroxisome proliferator-activated receptor gamma (PPARgamma) in a cell-free assay (Ki = 1.15 µM). Norbixin (47.7 mg/kg) attenuates hyperglycemia, hyperinsulinemia, and insulin resistance, as well as decreases serum lipid levels and cardiac levels of thiobarbituric acid reactive substances (TBARS) and glutathione (GSH) in a rat model of cardio-metabolic syndrome. It decreases serum levels of oxidized LDL and aortic protein oxidation, as well as reduces atherosclerotic area, in a rabbit model of cholesterol-induced atherosclerosis. Norbixin (0.1 and 1 mg/kg per day) reduces mercury-induced DNA damage in isolated rat hepatocytes and leukocytes. It also prevents photoreceptor degeneration in an Abca4-/- Rdh8-/- mouse model of age-related macular degeneration (AMD).Formal Name: 4,8,13,17-tetramethyl-2E,4E,6E,8E,10E,12E,14E,16E,18E-eicosanonaenedioic acid, hydrate. Molecular Formula: C24H28O4 . XH2O. Formula Weight: 380.5. Purity: >70%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Slightly soluble, Methanol: Slightly soluble, THF: Slightly soluble. SMILES: OC(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C(O)=O)=O. InChi Code: InChI=1S/C24H28O4/c1-19(11-7-13-21(3)15-17-23(25)26)9-5-6-10-20(2)12-8-14-22(4)16-18-24(27)28/h5-18H,1-4H3,(H,25,26)(H,27,28)/b6-5+,11-7+,12-8+,17-15+,18-16+,19-9+,20-10+,21-13+,22-14+. InChi Key: ZVKOASAVGLETCT-UOGKPENDSA-N. Origin: Synthetic.
Keywords: 4,8,13,17-tetramethyl-2E,4E,6E,8E,10E,12E,14E,16E,18E-eicosanonaenedioic acid, hydrate
Supplier: Cayman Chemical
Supplier-Nr: 40132

Properties

Application: Bioactive carotenoid
MW: 380.5 D
Formula: C24H28O4 . XH2O
Purity: >70%
Format: Solid

Database Information

Handling & Safety

Storage: -80°C
Shipping: -80°C (International: -80°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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