Marein

Marein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay33213-1 1 mg -

6 - 10 business days*

66.00€
Cay33213-5 5 mg -

6 - 10 business days*

263.00€
Cay33213-10 10 mg -

6 - 10 business days*

427.00€
Cay33213-25 25 mg -

6 - 10 business days*

739.00€
 
Marein is a glucoside chalcone that has been found in C. tinctoria and has diverse biological... more
Product information "Marein"
Marein is a glucoside chalcone that has been found in C. tinctoria and has diverse biological activities, including antioxidant, enzyme inhibitory, antidiabetic, and anti-inflammatory properties. It scavenges DPPH (Cay-14805) radicals (IC50 = 48.35 µM) in a cell-free assay and is an inhibitor of EGFR (IC50 = 19.94 µM). Marein (50 mg/kg) reduces fasting blood glucose and fasting serum levels of insulin, triglycerides, LDL cholesterol, and total cholesterol in diabetic db/db mice. It also reduces serum and renal IL-6 and chemokine (C-C motif) ligand 2 (CCL2) levels, as well as decreases kidney fibrosis, in db/db mice.Formal Name: (2E)-3-(3,4-dihydroxyphenyl)-1-[4-(beta-D-glucopyranosyloxy)-2,3-dihydroxyphenyl]-2-propen-1-one. CAS Number: 535-96-6. Molecular Formula: C21H22O11. Formula Weight: 450.4. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: soluble. lambdamax: 383 nm. SMILES: OC[C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC2=C(C(O)=C(C=C2)C(/C=C/C3=CC(O)=C(C=C3)O)=O)O. InChi Code: InChI=1S/C21H22O11/c22-8-15-18(28)19(29)20(30)21(32-15)31-14-6-3-10(16(26)17(14)27)11(23)4-1-9-2-5-12(24)13(25)7-9/h1-7,15,18-22,24-30H,8H2/b4-1+/t15-,18-,19+,20-,21-/m1/s1. InChi Key: XGEYXJDOVMEJNG-HTFDPZBKSA-N. Origin: Plant/Senecio cineraria.
Keywords: (2E)-3-(3,4-dihydroxyphenyl)-1-[4-(beta-D-glucopyranosyloxy)-2,3-dihydroxyphenyl]-2-propen-1-one
Supplier: Cayman Chemical
Supplier-Nr: 33213

Properties

Application: Bioactive glucoside chalcone
MW: 450.4 D
Formula: C21H22O11
Purity: >95%
Format: Crystalline Solid

Database Information

CAS : 535-96-6| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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