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Linoleic acid-d11 is intended for use as an internal standard for the quantification of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) by GC- or LC-MS. Linoleic acid is an essential omega-6 polyunsaturated fatty acid (PUFA). It is the most abundant PUFA in a variety of foods, and dietary sources of linoleic acid include vegetable oils, meats, nuts, seeds, and eggs. Linoleic acid (30 µM) increases migration of IEC-6 rat intestinal epithelial cells in a wound healing assay. Rats fed a linoleate-deficient diet exhibit decreased body weight and an increased ratio of eicosatrienoate to arachidonate in liver and serum phospholipids compared with rats fed a control diet, as well as mild scaling of forepaw skin.Formal Name: 9Z,12Z-octadecadienoic-14,14',15,15',16,16',17,17',18,18,18-d11 acid. Synonyms: C18:2(9Z,12Z)-d11, C18:2 n-6-d11, FA 18:2-d11, 9,12-Octadecadienoic Acid-d11, Telfairic Acid-d11. Molecular Formula: C18H21D11O2. Formula Weight: 291.5. Purity: >99% deuterated forms (d1-d11). Formulation: (Request formulation change), A solution in methyl acetate. Solubility: 0.15 M Tris-HCl pH 8.5: 1 mg/ml, DMF: 100 mg/ml, DMSO: 100 mg/ml, Ethanol: 100 mg/ml, PBS (pH 7.2): 100 µg/ml. SMILES: [2H]C(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])([2H])/C=C\C/C=C\CCCCCCCC(O)=O. InChi Code: InChI=1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9-/i1D3,2D2,3D2,4D2,5D2. InChi Key: OYHQOLUKZRVURQ-JPIWGEEBSA-N. Side Chain Carbon Sum: 18:2.
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