Linoleic Acid-13C18

Linoleic Acid-13C18 is intended for use as an internal standard for the quantification of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) by GC- or LC-MS. Linoleic acid is an essential omega-6 polyunsaturated fatty acid (PUFA). It is the most abundant PUFA in a variety of foods, and dietary sources of linoleic acid include vegetable oils, meats, nuts, seeds, and eggs. Linoleic acid (30 µM) increases migration of IEC-6 rat intestinal epithelial cells in a wound healing assay. Rats fed a linoleate-deficient diet exhibit decreased body weight and an increased ratio of eicosatrienoate to arachidonate in liver and serum phospholipids compared with rats fed a control diet, as well as mild scaling of forepaw skin.Formal Name: (9Z,12Z)-9,12-octadecadienoic-1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18-13C18 acid. CAS Number: 287111-25-5. Synonyms: C18:2(9Z,12Z)-13C18, C18:2 n-6-13C18, FA 18:2-13C, 9,12-Octadecadienoic Acid-13C18, Telfairic Acid-13C18. Molecular Formula: [13C]18H32O2. Formula Weight: 298.3. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: 0.15 M Tris-HCl pH 8.5: 1 mg/ml, DMF: 100 mg/ml, DMSO: 100 mg/ml, Ethanol: 100 mg/ml, PBS (pH 7.2): 100µg/ml. SMILES: O[13C]([13CH2][13CH2][13CH2][13CH2][13CH2][13CH2][13CH2]/[13CH]=[13CH]\[13CH2]/[13CH]=[13CH]\[13CH2][13CH2][13CH2][13CH2][13CH3])=O. InChi Code: InChI=1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9-/i1+1,2+1,3+1,4+1,5+1,6+1,7+1,8+1,9+1,10+1,11+1,12+1,13+1,14+1,15+1,16+1,17+1,18+1. InChi Key: OYHQOLUKZRVURQ-AZEGGMGZSA-N.