Kaempferol 3-glucuronide

Kaempferol 3-glucuronide is a flavonol glycoside that has been found in Fragaria and an active metabolite of kaempferol (Cay-11852) that has diverse biological activities. It is formed from kaempferol primarily in the small intestine. Kaempferol 3-glucuronide (0.1, 1, and 10 µM) induces Akt activity in mouse liver homogenates and increases glucose consumption in HepG2 cells. It inhibits the production of reactive oxygen species (ROS) induced by fMLP (Cay-21495) in isolated human neutrophils when used at concentrations of 1 and 10 µM.Formal Name: 5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-3-yl beta-D-glucopyranosiduronic acid. CAS Number: 22688-78-4. Synonyms: Kaempferol 3-O-beta-glucuronide. Molecular Formula: C21H18O12. Formula Weight: 462.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble. lambdamax: 268, 354 nm. SMILES: O=C(C(O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)C(O)=O)=C(C2=CC=C(C=C2)O)OC3=CC(O)=C4)C3=C4O. InChi Code: InChI=1S/C21H18O12/c22-8-3-1-7(2-4-8)17-18(13(25)12-10(24)5-9(23)6-11(12)31-17)32-21-16(28)14(26)15(27)19(33-21)20(29)30/h1-6,14-16,19,21-24,26-28H,(H,29,30)/t14-,15-,16+,19-,21+/m0/s1. InChi Key: FNTJVYCFNVUBOL-ZUGPOPFOSA-N. Origin: Plant/Styphnolobium japonicum.