Isovaleryl-L-carnitine-d3 (chloride)

Isovaleryl-L-carnitine-d3 (chloride)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay26574-1 1 mg -

6 - 10 business days*

153.00€
Cay26574-5 5 mg -

6 - 10 business days*

609.00€
 
Isovaleryl-L-carnitine-d3 is intended for use as an internal standard for the quantification of... more
Product information "Isovaleryl-L-carnitine-d3 (chloride)"
Isovaleryl-L-carnitine-d3 is intended for use as an internal standard for the quantification of isovaleryl-L-carnitine (Cay-26555) by GC- or LC-MS. Isovaleryl-L-carnitine is a naturally occurring acylcarnitine that is formed via metabolism of L-leucine. It increases survival and decreases apoptosis in hepatocyte growth factor-deprived murine C2.8 hepatocytes when used at a concentration of 1 mM. Isovaleryl-L-carnitine inhibits amino acid deprivation-induced proteolysis and autophagy in isolated perfused rat liver when used at concentrations of 77 and 100 µM, respectively. Increased levels of isovaleryl carnitine are associated with isovaleryl-CoA dehydrogenase deficiency (isovaleric acidemia).Formal Name: (R)-3-carboxy-N,N-dimethyl-N-(methyl-d3)-2-((3-methylbutanoyl)oxy)propan-1-aminium, monochloride. Synonyms: CAR 5:0-d3, C5:0 Carnitine-d3, L-Carnitine isovaleryl ester-d3, L-Isovalerylcarnitine-d3. Molecular Formula: C12H21D3NO4 . Cl. Formula Weight: 284.8. Purity: >99% deuterated forms (d1-d3). Formulation: (Request formulation change), A solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 25 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: OC(C[C@H](C[N+](C([2H])([2H])[2H])(C)C)OC(CC(C)C)=O)=O.[Cl-]. InChi Code: InChI=1S/C12H23NO4.ClH/c1-9(2)6-12(16)17-10(7-11(14)15)8-13(3,4)5,/h9-10H,6-8H2,1-5H3,1H/t10-,/m1./s1/i3D3,. InChi Key: HWDFIOSIRGUUSM-QVKFCBEOSA-N.
Keywords: L-Isovalerylcarnitine-d3, (R)-3-carboxy-N,N-dimethyl-N-(methyl-d3)-2-((3-methylbutanoyl)oxy)propan-1-aminium, monochloride
Supplier: Cayman Chemical
Supplier-Nr: 26574

Properties

Application: GC-MS, LC-MS, quantification, internal standard, autophagy inhibitor
MW: 284.8 D
Formula: C12H21D3NO4 . Cl
Purity: >99% deuterated forms (d1-d3)
Format: Solid

Database Information

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H317, H319
P Phrases: P261, P264, P272, P280, P321, P302+P352, P305+P351+P338, P333+P313, P337+P313, P362+P364, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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