IR-117-17

IR-117-17
NEW
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay40420-5 5 mg -

6 - 10 business days*

473.00€
Cay40420-10 10 mg -

6 - 10 business days*

851.00€
 
IR-117-17 is an ionizable cationic and biodegradable amino lipid. It has been used in the... more
Product information "IR-117-17"
IR-117-17 is an ionizable cationic and biodegradable amino lipid. It has been used in the generation of lipid nanoparticles (LNPs). Nebulized administration of LNPs containing IR-117-17 and the cationic lipid 1,2-dioleoyl-2-trimethylammoniumpropane (1,2-DOTAP, Cay-15110), among other components, and encapsulating reporter mRNA induce luciferase luminescence in the lung and nasal passages in mice. Nebulized administration of the same LNP formulation but encapsulating Cre mRNA induces the expression of Cre in cells of the large and small airways, as well as alveolar macrophages and epithelial cells, in Ai14 mice engineered to express the fluorescent protein tdTomato upon translation of Cre.InChI: InChI=1S/C59H110N2O5/c1-5-9-13-15-17-19-21-23-25-27-29-31-33-35-39-47-58(63)65-53-42-37-38-46-57(62)56(55-60-49-44-52-61(50-11-7-3)51-12-8-4)45-41-43-54-66-59(64)48-40-36-34-32-30-28-26-24-22-20-18-16-14-10-6-2/h17-20,23-26,56-57,60,62H,5-16,21-22,27-55H2,1-4H3/b19-17-,20-18-,25-23-,26-24- InChIKey: LPCMSGYAOKCGLI-XHFJISOBSA-N SMILES: CCCCC/C=C\C/C=C\CCCCCCCC(OCCCCCC(C(CCCCOC(CCCCCCC/C=C\C/C=C\CCCCC)=O)CNCCCN(CCCC)CCCC)O)=O
Keywords: A10-LIN, 5-(((3-(dibutylamino)propyl)amino)methyl)-6-hydroxyundecane-1,11-diyl (9Z,9'Z,12Z,12'Z)-bis(octadeca-9,12-dienoate)
Supplier: Cayman Chemical
Supplier-Nr: 40420

Properties

Application: Ionizable cationic, biodegradable amino lipid, LNP formation
MW: 927.5 D
Formula: C59H110N2O5
Purity: >95%
Format: Solution

Database Information

CAS : 2940241-38-1| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H319, H333
P Phrases: P210, P233, P240, P241, P242, P243, P264, P280, P303+361+353, P304+312, P305+351+338, P337+313, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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