Ganoderenic Acid D

Ganoderenic acid D is a triterpenoid originally isolated from G. lucidum and has diverse biological activities. It inhibits angiotensin-converting enzyme (ACE, IC50 = 734 µM). Ganoderenic acid D is cytotoxic to HepG2 liver, HeLa cervical, and Caco-2 colon cancer cells (IC50s = 0.14, 0.18, and 0.26 mg/ml, respectively). It inhibits LPS-induced nitric oxide (NO) production in BV-2 microglia (IC50 = 13.77 µM).Formal Name: (7beta,20E)-7-hydroxy-3,11,15,23-tetraoxo-lanosta-8,20(22)-dien-26-oic acid. CAS Number: 100665-43-8. Molecular Formula: C30H40O7. Formula Weight: 512.6. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: Soluble, Methanol: Soluble. SMILES: CC1(C)C(CCC2(C)C3=C(C4(C(CC(C4(CC3=O)C)/C(C)=C/C(CC(C)C(O)=O)=O)=O)C)[C@@H](O)CC12)=O. InChi Code: InChI=1S/C30H40O7/c1-15(10-17(31)11-16(2)26(36)37)18-12-23(35)30(7)25-19(32)13-21-27(3,4)22(34)8-9-28(21,5)24(25)20(33)14-29(18,30)6/h10,16,18-19,21,32H,8-9,11-14H2,1-7H3,(H,36,37)/b15-10+/t16?,18?,19-,21?,28?,29?,30?/m0/s1. InChi Key: JGWQYLZHPPFHEH-UJSUDUSHSA-N. Origin: Fungus/Ganoderma sp..