Eicosapentaenoyl 1-propanol-2-amide

Monoacylglycerols (MAGs) of omega-3 polyunsaturated fatty acids have diverse physiological and health effects. In particular, MAGs containing docosahexaenoic acid (Cay-90310) or eicosapentaenoic acid (EPA, Cay-90110) have anti-proliferative properties against colon and lung cancer cell lines. Eicosapentaenoyl 1-propanol-2-amide is an EPA-containing MAG amide analog that inhibits the growth of human lung carcinoma A549 cells, producing 98.4% growth inhibition when applied at 3 µM. It is an analog of eicosapentaenoyl ethanolamide (Cay-10964), a natural N-acylethanolamide that impacts aging and inflammation.Formal Name: N-(2-hydroxy-1-methylethyl)-5Z,8Z,11Z,14Z,17Z-eicosapentaenamide. CAS Number: 1638355-66-4. Molecular Formula: C23H37NO2. Formula Weight: 359.6. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2) (1:2): 0.3 mg/ml. SMILES: CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(NC(CO)C)=O. InChi Code: InChI=1S/C23H37NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-23(26)24-22(2)21-25/h4-5,7-8,10-11,13-14,16-17,22,25H,3,6,9,12,15,18-21H2,1-2H3,(H,24,26)/b5-4-,8-7-,11-10-,14-13-,17-16-. InChi Key: XOYVLIGJHWVUFH-JEBPEJKESA-N.