DSPE-PEG(2000)-amine (sodium salt)

DSPE-PEG(2000)-amine is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE (DSPE, Cay-15095). It has been used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents. DSPE-PEG(2000)-amine has also been used in the synthesis of fluorescein isothiocyanate-loaded mesoporous silica nanoparticles for imaging applications. It can be conjugated to a variety of functional molecules for improved cellular targeting and uptake of DSPE-PEG(2000)-amine-containing nanoparticles.Formal Name: alpha-[(9R)-6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxooctadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphanonacos-1-yl]-omega-(2-aminoethoxy)-poly(oxy-1,2-ethanediyl), monosodium salt. Synonyms: 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000], 1,2-distearoyl-sn-glycero-3-PE-N-[amino(polyethylene glycol)-2000], 1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-N-[amino(polyethylene glycol)-2000], 1,2-DSPE-PEG(2000)-amine. Molecular Formula: (C2H4O)n C44H86N2O10P . Na. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 11 mg/ml, Ethanol: 20 mg/ml. SMILES: O=[P](OCCNC(OCCOCCN)=O)(O)OCC(COC(CCCCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCCCC)=O.[Na].