Docosanoic Acid-d43

Docosanoic acid-d43 is intended for use as an internal standard for the quantification of docosanoic acid (Cay-9000338) by GC- or LC-MS. Docosanoic acid is a long-chain saturated fatty acid. It has been found in peanut and M. oleifera seed oils. It inhibits the double-stranded DNA binding activity of p53 through a direct interaction with the DNA binding domain (Kd = 12 nM). Docosanoic acid inhibits rat DNA polymerase beta and human DNA polymerase lambda activity in cell-free enzyme assays when used at a concentration of 100 µM and inhibits human DNA topoisomerase I and II relaxation activity at a concentration of 25 µM. Liver levels of docosanoic acid are reduced in rats fed a high-fat or a high-fat and high-cholesterol diet but not a high-cholesterol only diet. Formulations containing docosanoic acid have been used in hair conditioner and moisturizers.CAS Number: 29823-26-5. Synonyms: Behenic Acid-d43, C22:0-d43, DCA-d43. Molecular Formula: C22HD43O2. Formula Weight: 383.9. Purity: >99% deuterated forms (d1-d43). Formulation: (Request formulation change), A solid. Solubility: DMF: 3 mg/ml, DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml. SMILES: [2H]C(C([2H])([2H])C(O)=O)([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H]. InChi Code: InChI=1S/C22H44O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h2-21H2,1H3,(H,23,24)/i1D3,2D2,3D2,4D2,5D2,6D2,7D2,8D2,9D2,10D2,11D2,12D2,13D2,14D2,15D2,16D2,17D2,18D2,19D2,20D2,21D2. InChi Key: UKMSUNONTOPOIO-MSWDUVJOSA-N.