Deoxycorticosterone Acetate

Deoxycorticosterone acetate (DOCA) is a corticosteroid. It is an acetylated form of deoxycorticosterone (11-deoxy corticosterone, Cay-22916). DOCA, in combination with saline via the drinking water, has commonly been used in rodents as a model of salt-sensitive hypertension, characterized by increases in sympathetic nervous system activity, imbalances in the renin-angiotensin system (RAS), and cardiac remodeling.Formal Name: 21-(acetyloxy)-pregn-4-ene-3,20-dione. CAS Number: 56-47-3. Synonyms: DOCA. Molecular Formula: C23H32O4. Formula Weight: 372.5. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: 10 mg/ml, DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml, DMSO: 2 mg/ml, Ethanol: 1 mg/ml. lambdamax: 240 nm. SMILES: O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@H]4C(COC(C)=O)=O)=C1. InChi Code: InChI=1S/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17-,18-,19-,20+,22-,23-/m0/s1. InChi Key: VPGRYOFKCNULNK-ACXQXYJUSA-N.