CP-LC-1447

CP-LC-1447
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay41922-5 5 mg - -

6 - 10 business days*

204.00€
Cay41922-10 10 mg - -

6 - 10 business days*

326.00€
Cay41922-25 25 mg - -

6 - 10 business days*

715.00€
 
Lipid CP-LC-1447 is an ionizable cationic amino lipid derived from homocysteine, a naturally... more
Product information "CP-LC-1447"
Lipid CP-LC-1447 is an ionizable cationic amino lipid derived from homocysteine, a naturally occurring amino acid. This lipid has demonstrated an efficient delivery and high protein expression of different kinds of RNA (mRNA, cRNA and saRNA) in vivo. Moreover, using a typical LNP formulation (IL/Ch/DOPE/PEG: 50/38.5/10/1.5), it has shown to induce specific spleen targeting much more efficiently that other commercial alternatives through IV injection, with no signs of toxicity.Formal Name: dioctyl 3,3'-((8-((1-((2-(1H-imidazol-1-yl)ethyl)amino)-1-oxo-4-((3-oxo-3-(tridecyloxy)propyl)thio)butan-2-yl)amino)-8-oxooctane-1,3-diyl)bis(sulfanediyl))dipropionate. Molecular Formula: C55H100N4O8S3. Formula Weight: 1041.6. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Ethanol: Soluble: >10 mg/ml. SMILES: O=C(NCCN1C=CN=C1)C(CCSCCC(OCCCCCCCCCCCCC)=O)NC(CCCCC(CCSCCC(OCCCCCCCC)=O)SCCC(OCCCCCCCC)=O)=O. InChi Code: InChI=1S/C55H100N4O8S3/c1-4-7-10-13-16-17-18-19-20-23-28-41-66-53(62)34-46-69-44-32-50(55(64)57-37-39-59-38-36-56-48-59)58-51(60)30-25-24-29-49(70-47-35-54(63)67-42-27-22-15-12-9-6-3)31-43-68-45-33-52(61)65-40-26-21-14-11-8-5-2/h36,38,48-50H,4-35,37,39-47H2,1-3H3,(H,57,64)(H,58,60). InChi Key: FHVDYXCHVWHIHK-UHFFFAOYSA-N.
Keywords: dioctyl 3,3'-((8-((1-((2-(1H-imidazol-1-yl)ethyl)amino)-1-oxo-4-((3-oxo-3-(tridecyloxy)propyl)thio)butan-2-yl)amino)-8-oxooctane-1,3-diyl)bis(sulfanediyl))dipropionate
Supplier: Cayman Chemical
Supplier-Nr: 41922

Properties

Application: Ionizable cationic homocysteine derived amino lipid, LNP formation
MW: 1041.6 D
Formula: C55H100N4O8S3
Purity: >95%
Format: Solution

Database Information

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H319, H333
P Phrases: P210, P233, P240, P241, P242, P243, P264, P280, P303+361+353, P304+312, P305+351+338, P337+313, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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