Chrysoeriol

Chrysoeriol is a flavonoid that has been found in Capsicum and has diverse biological activities. It is active against the Gram-positive bacteria E. faecalis, B. subtilis, and S. aureus (MICs = 1, 1, and 0.25 µg/ml, respectively) and the Gram-negative bacteria P. aeruginosa, K. pneumoniae, and E. coli (MICs = 0.12, 0.25, and 0.06 µg/ml, respectively). Chrysoeriol (7.5, 15, and 30 µM) induces cell cycle arrest at the G1 phase and autophagy in A549 lung cancer cells. It reduces LPS-induced production of IL-6, IL-1beta, and TNF-alpha in RAW 264.7 cells when used at a concentration of 20 µM. Chrysoeriol (20 mg/kg) reduces plasma glucose, total cholesterol, free fatty acid, and phospholipid levels in a rat model of diabetes induced by streptozotocin (STZ, Cay-13104).Formal Name: 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one. CAS Number: 491-71-4. Synonyms: 3'-methoxy Apigenin, Luteolin 3'-methyl ether. Molecular Formula: C16H12O6. Formula Weight: 300.3. Purity: >90%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 20 mg/ml, Ethanol: Slightly Soluble. lambdamax: 244, 269, 345 nm. SMILES: O=C1C=C(C2=CC(OC)=C(O)C=C2)OC3=C1C(O)=CC(O)=C3. InChi Code: InChI=1S/C16H12O6/c1-21-14-4-8(2-3-10(14)18)13-7-12(20)16-11(19)5-9(17)6-15(16)22-13/h2-7,17-19H,1H3. InChi Key: SCZVLDHREVKTSH-UHFFFAOYSA-N. Origin: Plant/Suaeda salsa (L.) Pall. Illustr..