Benzydamine (hydrochloride)

Benzydamine (hydrochloride)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay39808-5 5 g -

6 - 10 business days*

40.00€
Cay39808-10 10 g -

6 - 10 business days*

75.00€
Cay39808-25 25 g -

6 - 10 business days*

179.00€
 
Benzydamine is a non-steroidal anti-inflammatory drug (NSAID). It decreases the viability of... more
Product information "Benzydamine (hydrochloride)"
Benzydamine is a non-steroidal anti-inflammatory drug (NSAID). It decreases the viability of THP-1 monocytes, Saos-2 osteosarcoma, and HGF-1 gingival cancer cells (IC50s = 59.08, 30.79, and 52.06 µg/ml, respectively). Benzydamine (10 µg/ml) reduces LPS-induced increases in the levels of IL-6 and TNF-alpha secreted by THP-1 cells. It decreases the levels of prostaglandin E2 (PGE2, Cay-14010) and PGF1alpha (Cay-15010) in unstimulated or IL-1beta- or TNF-alpha-stimulated primary human gingival fibroblasts when used at a concentration of 1 µM. Benzydamine (100 mg/kg) reduces hydrochloric acid levels and increases mucin levels in gastric juices isolated from rats. It inhibits carrageenan-induced paw edema in rats when administered orally at a dose of 60 mg/kg or applied topically at 3% (w/w). Formulations containing benzydamine have been used in the treatment of acute sore throat. This product is also available as an analytical reference standard (Cay-15161).Formal Name: N,N-dimethyl-3-[[1-(phenylmethyl)-1H-indazol-3-yl]oxy]-1-propanamine, monohydrochloride. CAS Number: 132-69-4. Molecular Formula: C19H23N3O . HCl. Formula Weight: 345.9. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: Soluble. SMILES: CN(C)CCCOC1=NN(CC2=CC=CC=C2)C3=C1C=CC=C3.Cl. InChi Code: InChI=1S/C19H23N3O.ClH/c1-21(2)13-8-14-23-19-17-11-6-7-12-18(17)22(20-19)15-16-9-4-3-5-10-16,/h3-7,9-12H,8,13-15H2,1-2H3,1H. InChi Key: HNNIWKQLJSNAEQ-UHFFFAOYSA-N.
Keywords: N,N-dimethyl-3-[[1-(phenylmethyl)-1H-indazol-3-yl]oxy]-1-propanamine, monohydrochloride
Supplier: Cayman Chemical
Supplier-Nr: 39808

Properties

Application: NSAID, COX inhibitor
MW: 345.9 D
Formula: C19H23N3O . HCl
Purity: >95%
Format: Solid

Database Information

CAS : 132-69-4| Matching products
KEGG ID : K00509 | Matching products

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H302, H315, H319
P Phrases: P264, P270, P280, P321, P330, P301+P310, P302+P352, P305+P351+P338, P332+P313, P337+P313, P362+P364, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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