BAmP-O16B

BAmP-O16B is an ionizable cationic amino lipid that has been used in the generation of lipid nanoparticles (LNPs). LNPs containing BAmP-O16B and encapsulating NSA-inactivated RNase A reduce the viability of SiHa and HeLa cancer cells, but not non-cancerous NIH3T3 and HEK293T cells, upon intracellular reactivation of RNase A by glutathione (GSH).Formal Name: bis(2-(dodecyldisulfaneyl)ethyl) 3,3'-((3-(4-(3-((3-(2-(dodecyldisulfaneyl)ethoxy)-3-oxopropyl)amino)propyl)piperazin-1-yl)propyl)azanediyl)dipropionate. Molecular Formula: C61H120N4O6S6. Formula Weight: 1198.0. Purity: >98%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: Chloroform: Soluble, Dichloromethane: Soluble. SMILES: CCCCCCCCCCCCSSCCOC(CCN(CCC(OCCSSCCCCCCCCCCCC)=O)CCCN1CCN(CCCNCCC(OCCSSCCCCCCCCCCCC)=O)CC1)=O. InChi Code: InChI=1S/C61H120N4O6S6/c1-4-7-10-13-16-19-22-25-28-31-53-72-75-56-50-69-59(66)36-40-62-39-34-41-64-46-48-65(49-47-64)43-35-42-63(44-37-60(67)70-51-57-76-73-54-32-29-26-23-20-17-14-11-8-5-2)45-38-61(68)71-52-58-77-74-55-33-30-27-24-21-18-15-12-9-6-3/h62H,4-58H2,1-3H3. InChi Key: ONNUDORABXGDRF-UHFFFAOYSA-N.