Anacardic Acid triene

Anacardic acid triene is a polyunsaturated form of anacardic acid (Cay-13144) that has been found in cashew nut shell liquid. It inhibits soybean lipoxygenase-1 (IC50 = 60 µM in an enzyme assay) and inhibits superoxide production by xanthine oxidase by 82% when used at a concentration of 88 µM. Anacardic acid triene is active against S. mutans and S. aureus, including the methicillin-resistant S. aureus (MRSA) strain ATCC 33591 (MICs = 1.56, 6.25, and 6.25 µg/ml, respectively). It also inhibits NADH oxidase (IC50 = 1.3 µg/ml), an enzyme involved in bacterial respiration. Anacardic acid triene is molluscicidal, inducing toxicity in B. glabrata (LC50 = 0.35 ppm), but is inactive against S. mansoni parasites.Formal Name: 2-hydroxy-6-(8Z,11Z)-8,11,14-pentadecatrien-1-yl-benzoic acid. CAS Number: 103904-73-0. Synonyms: Anacardic Acid 15:3. Molecular Formula: C22H30O3. Formula Weight: 342.5. Purity: >98%. Formulation: (Request formulation change), A neat oil. Solubility: DMF: 20 mg/mL, DMSO: 15 mg/mL, Ethanol: 22 mg/mL, Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL. lambdamax: 244, 313 nm. SMILES: OC1=CC=CC(CCCCCCC/C=C\C/C=C\CC=C)=C1C(O)=O. InChi Code: InChI=1S/C22H30O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-17-15-18-20(23)21(19)22(24)25/h2,4-5,7-8,15,17-18,23H,1,3,6,9-14,16H2,(H,24,25)/b5-4-,8-7-. InChi Key: QUVGEKPNSCFQIR-UTOQUPLUSA-N. Origin: Plant/Anacardium occidentale.