Altrenogest

Altrenogest is a synthetic progestin and an agonist of progesterone and androgen receptors (EC50s = 0.64 and 0.63 nM, respectively, in S. cerevisiae cells expressing human receptors). In vivo, altrenogest (20 mg/animal per day) reduces testicular weight, sperm content, and serum levels of luteinizing hormone and testosterone in boars. Altrenogest (0.044 mg/kg) increases serum concentrations of equine chorionic gonadotropin and embryonic size in pregnant mares. It also decreases genital perfusion and increases estrus cycle length in mares. Formulations containing altrenogest have been used to synchronize estrus in horses and pigs.Formal Name: (17beta)-17-hydroxy-17-(2-propen-1-yl)-estra-4,9,11-trien-3-one. CAS Number: 850-52-2. Synonyms: Allyltrenbolone, DRC 6246, RU 2267. Molecular Formula: C21H26O2. Formula Weight: 310.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 2 mg/ml, DMSO: 0.1 mg/ml, Ethanol: 20 mg/ml, Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml. lambdamax: 242, 342 nm. SMILES: O=C1CCC2=C3[C@@]([C@@](CC[C@@]4(O)CC=C)([H])[C@]4(C)C=C3)([H])CCC2=C1. InChi Code: InChI=1S/C21H26O2/c1-3-10-21(23)12-9-19-18-6-4-14-13-15(22)5-7-16(14)17(18)8-11-20(19,21)2/h3,8,11,13,18-19,23H,1,4-7,9-10,12H2,2H3/t18-,19+,20+,21+/m1/s1. InChi Key: VWAUPFMBXBWEQY-ANULTFPQSA-N.