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Adrenic acid is a naturally occurring polyunsaturated fatty acid (PUFA) formed through a 2-carbon chain elongation of arachidonic acid. It is present in the adrenal glands, brain, testis, and kidney. Although there is trace metabolism of adrenic acid in the forebrain, the renal medulla is the only tissue which readily metabolizes the acid through cyclooxygenase activity. The primary metabolite of adrenic acid in the rabbit kidney is 1a,1b-dihomo prostaglandin E2.Formal Name: 7Z,10Z,13Z,16Z-docosatetraenoic acid. CAS Number: 28874-58-0. Synonyms: FA 22:4. Molecular Formula: C22H36O2. Formula Weight: 332.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: 0.15 M Tris-HCl pH 8.5: >1 mg/ml (from Oleic Acid), DMF: >100 mg/ml (from Oleic Acid), DMSO: >100 mg/ml (from Oleic Acid), Ethanol: >100 mg/ml (from Oleic Acid), PBS pH 7.2: <100 µg/ml (from Oleic Acid). SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(=O)O. InChi Code: InChI=1S/C22H36O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-21H2,1H3,(H,23,24)/b7-6-,10-9-,13-12-,16-15-. InChi Key: TWSWSIQAPQLDBP-DOFZRALJSA-N. Side Chain Carbon Sum: 22:4.
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