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Eupafolin
Item number: Cay40138-1
Eupafolin is a flavonoid that has been found in E. adenophorum and has diverse biological activities. It inhibits iron-dependent lipid peroxidation in a cell-free assay (IC50 = 7.9 µM). Eupafolin (50-150 µM) inhibits prion protein 106-126 (PrP106-126) aggregation in a cell-free assay and reduces PrP106-126-induced...
| Keywords: | 6-Methoxyluteolin, Nepetin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-methoxy-4H-1-benzopyran-4-one |
| Application: | Bioactive flavonoid |
| CAS | 520-11-6 |
| MW: | 316.3 D |
From 81.00€
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Ombuin
Item number: Cay40217-1
Ombuin is a flavonoid that has been found in B. balsamifera and has diverse biological activities. It is an antagonist of M1 muscarinic acetylcholine receptors (mAChRs, Ki = 42 µM in CHO-K1 cells expressing the human receptor). Ombuin is cytotoxic to HepG2 hepatocellular carcinoma cells (IC50 = 1.5 µg/ml). In vivo,...
| Keywords: | NSC 675952, 3,5-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-methoxy-4H-1-benzopyran-4-one |
| Application: | Bioactive flavonoid |
| CAS | 529-40-8 |
| MW: | 330.3 D |
From 35.00€
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C14-A1
Item number: Cay40256-1
C14-A1 is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs). LNPs containing C14-A1 and encapsulating mRNA expressing forkhead box protein P3 (FOXP3) increase FOXP3 levels in primary human T cells. LNPs containing C14-A1 and encapsulating mRNA expressing FOXP3 also reduce...
| Keywords: | 1,1'-((5-(4-(2-((5-(bis(2-hydroxytetradecyl)amino)pentyl)(2-hydroxytetradecyl)amino)ethyl)piperazin-1-yl)pentyl)azanediyl)... |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 1361.4 D |
From 81.00€
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Artemitin
Item number: Cay40269-10
Artemitin is a flavonoid that has been found in A. annua and has diverse biological activities. It scavenges peroxyl radicals in a cell-free assay in a concentration-dependent manner. Artemitin inhibits 5-lipoxygenase (5-LO) with an IC50 value of 54.6 µM. It is active against P. falciparum (IC50 = 26 µM). Artemitin...
| Keywords: | Artemetin, Artemisetin, 2-(3,4-dimethoxyphenyl)-5-hydroxy-3,6,7-trimethoxy-4H-1-benzopyran-4-one |
| Application: | Bioactive flavonoid |
| CAS | 479-90-3 |
| MW: | 388.4 D |
From 195.00€
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5,7,3',4'-Tetramethoxyflavone
Item number: Cay40272-100
5,7,3',4'-Tetramethoxyflavone is a flavone that has been found in M. paniculata and has diverse biological activities. It selectively inhibits multidrug resistance-associated protein 1 (MRP1) over MRP2 (IC50s = 7.9 and >50 µM, respectively). 5,7,3',4'-Tetramethoxyflavone (0.03-30 µM) inhibits LPS-induced nitric...
| Keywords: | 5,7,3',4'-tetramethyl Luteolin ether, Methoxyluteolin, Tetramethyl camphoral,... |
| Application: | Bioactive flavone |
| CAS | 855-97-0 |
| MW: | 342.3 D |
From 48.00€
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CL15F6
Item number: Cay40345-1
CL15F6 is an ionizable cationic lipid (pKa = 6.75). It has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA and polymer-lipid hybrid nanoparticles for the delivery of plasmid DNA in vitro.Formal Name: 1-methyl-4-piperidinecarboxylic acid,...
| Keywords: | 1-methyl-4-piperidinecarboxylic acid, 11-[(2-hexyl-1-oxodecyl)oxy]-5-[6-[(2-hexyl-1-oxodecyl)oxy]hexyl]-5-hydroxyundecyl... |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 2766493-40-5 |
| MW: | 906.5 D |
From 95.00€
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BAmP-O16B
Item number: Cay40473-10
BAmP-O16B is an ionizable cationic amino lipid that has been used in the generation of lipid nanoparticles (LNPs). LNPs containing BAmP-O16B and encapsulating NSA-inactivated RNase A reduce the viability of SiHa and HeLa cancer cells, but not non-cancerous NIH3T3 and HEK293T cells, upon intracellular reactivation of...
| Keywords: | bis(2-(dodecyldisulfaneyl)ethyl)... |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 1198 D |
From 162.00€
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PPPDA-O16B
Item number: Cay40517-10
PPPDA-O16B is a disulfide bond-containing ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for plasmid delivery in vitro and in vivo. LNPs containing PPPDA-O16B and encapsulating plasmids encoding Ras/Rap1-specific endopeptidase (RRSP) increase RRSP levels and decrease Ras...
| Keywords: | bis(2-(dodecyldisulfaneyl)ethyl) 3,3'-(propylazanediyl)dipropionate |
| Application: | Disulfide bond-containing ionizable cationic lipid, LNP formation |
| MW: | 724.2 D |
From 162.00€
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6,6´-Trehalose Dioleate
Item number: Cay42212-1
| Application: | S |
| CAS | 338733-40-7 |
| MW: | 871,2 D |
From 95.00€
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Vitamin D3-d6
Item number: ISO-S15008.1
Isotope Incorporation: >98%
| Keywords: | Deuterium-labelled |
| Application: | Vitamin D receptor agonist, LC/MS internal standard |
| CAS | 67-97-0 |
From 517.00€
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8(Z),11(Z),14(Z)-Heptadecatrienal
Item number: Cay10005154-1
8(Z),11(Z),14(Z)-Heptadecatrienal is a polyunsaturated fatty aldehyde. It is formed from alpha-linolenic acid (Cay-90210, Cay-21910) via a 2(R)-hydroperoxy-9(Z),12(Z),15(Z)-octadecatrienoic acid intermediate. It is also a degradation product of 2(R)-hydroperoxy linolenic acid. 8(Z),11(Z),14(Z)-Heptadecatrienal (100...
| Keywords: | 17:3-al, all-cis-8,11,14-Heptadecatrienal, 8Z,11Z,14Z-heptadecatrienal |
| Application: | Polyunsaturated fatty aldehyde |
| CAS | 56797-44-5 |
| MW: | 248.4 D |
From 171.00€
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C6 Ceramide (d18:1/6:0) Alkyne
Item number: Cay24519-100
C6 Ceramide alkyne is an omega-alkyne derivative of C6 ceramide (Cay-62525). The terminal alkyne group can be used in click chemistry reactions to tag C6 ceramide with fluorescent or biotinylated labels for analysis of its metabolism and biological activity.Formal Name:...
| Keywords: | C6 Ceramide Alkyne, Cer(d18:1/6:0) Alkyne, Click Tag(TM) C6 Ceramide (d18:1/6:0) Alkyn, N-hexanoyl-D-erythro-Sphingosine... |
| Application: | omega-alkyne, click chemistry |
| MW: | 393.6 D |
40.00€
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