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Iloprost
Item number: Cay18215-1
Iloprost is a second generation structural analog of prostacyclin (PGI) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the human recombinant IP and EP1 receptors with a Ki of 11 nM. Iloprost constricts the isolated...
| Keywords: | Ciloprost, 6,9alpha-methylene-11alpha,15S-dihydroxy-16-methyl-prosta-5E,13E-dien-18-yn-1-oic acid |
| Application: | PGI analog |
| CAS | 78919-13-8 |
| MW: | 360.5 D |
From 35.00€
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Palmitoyl Ethanolamide
Item number: Cay90350-5
Palmitoyl ethanolamide (PEA) is an endogenous fatty N-acyl ethanolamine and a derivative of the endocannabinoid arachidonoyl ethanolamide (AEA, Cay-90050). It selectively activates peroxisome proliferator-activated receptor alpha (PPARalpha, EC50 = 3.1 µM) over PPARbeta/delta and PPARgamma in HeLa cells expressing...
| Keywords: | Palmidrol, PEA, N-(2-hydroxyethyl)-hexadecanamide |
| Application: | Bioactive lipid assays |
| CAS | 544-31-0 |
| MW: | 299.5 D |
From 44.00€
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Leukotriene E4
Item number: Cay20410-25
Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4, leaving only the cysteinyl group still attached to the fatty acid backbone. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). LTE4 is considerably less active (8 to 12-fold) than LTC4 in the biological activities...
| Keywords: | LTE4, 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 75715-89-8 |
| MW: | 439.6 D |
From 197.00€
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SQ 29,548
Item number: Cay19025-1
SQ 29,548 is a highly selective TP receptor antagonist which binds to the human recombinant TP receptor with a Ki of 4.1 nM. It inhibits the aggregation of washed human platelets induced by U-46619 with an IC50 of 0.06 µM. It antagonizes U-46619 induced contraction of rat and guinea pig tracheal, arterial, and...
| Keywords: | [1S-[1alpha,2alpha(Z),3alpha,4alpha]]-7-[3-[[2-[(phenylamino)carbonyl]hydrazino]methyl]-7-oxabicyclo[2.2.1]hept-2-yl]-5-he... |
| Application: | TP receptor antagonist |
| CAS | 98672-91-4 |
| MW: | 387.5 D |
From 116.00€
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Prostaglandin D2-d4
Item number: Cay312010-25
Prostaglandin D2-d4 (PGD2-d4) is intended for use as an internal standard for the quantification of PGD2 by GC- or LC-mass spectrometry. PGD2 is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of...
| Keywords: | PGD2-d4, 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 acid |
| Application: | Standard |
| CAS | 211105-29-2 |
| MW: | 356.5 D |
From 128.00€
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(±)12(13)-DiHOME
Item number: Cay10009832-100
(±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME (Cay-52450), a cytochrome P450-derived epoxide of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) also known as isoleukotoxin. It is formed from 12(13)-EpOME by soluble epoxide hydrolase (sEH) in neutrophils. 12(13)-DiHOME is toxic to Sf21 cells expressing sEH...
| Keywords: | Isoleukotoxin diol, 12,13-dihydroxy-9Z-octadecenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 263399-35-5 |
| MW: | 314.5 D |
From 44.00€
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2-Arachidonoyl Glycerol-d5
Item number: Cay362162-100
2-Arachidonoyl glycerol-d5 (2-AG-d5) is intended for use as an internal standard for the quantification of 2-AG (Cay-62160) by GC- or LC-MS. 2-AG is an endogenous agonist of the CB1 receptor. Unlike anandamide, 2-AG is present at relatively high levels in the central nervous system, it is the most abundant molecular...
| Keywords: | 2-AG-d5, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glycerol-1,1,2,3,3-d5 ester |
| Application: | Standard |
| CAS | 2522598-88-3 |
| MW: | 383.6 D |
From 121.00€
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(±)17-HDHA
Item number: Cay33650-25
(±)17-HDHA is an autoxidation product of docosahexaenoic acid (DHA, Cay-90310) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. 17(S)-HDHA (Cay-10009799) could be produced by enzymatic oxidation of DHA using soybean lipoxygenase (LO) and is the putative product of...
| Keywords: | (±)17-HDoHE, 17-hydroxy Docosahexaenoic Acid, 17-hydroxy DHA, (±)17-hydroxy-4Z,7Z,10Z,13Z,15E,19Z-docosahexaenoic acid |
| Application: | Oxidative stress marker |
| CAS | 90780-52-2 |
| MW: | 344.5 D |
From 92.00€
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13(S)-HODE-d4
Item number: Cay338610-25
13(S)-HODE-d4 is intended for use as an internal standard for the quantification of 13-HODE by GC- or LC-MS. (±)-13-HODE is formed via non-enzymatic oxidation of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909). 13(S)-HODE and 13(R)-HODE are formed by lipoxygenase- and cyclooxygenase-mediated oxidation of linoleic...
| Keywords: | 13S-hydroxy-9Z,11E-octadecadienoic-9,10,12,13-d4 acid |
| Application: | Standard |
| CAS | 139408-39-2 |
| MW: | 300.5 D |
From 184.00€
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10(S),17(S)-DiHDHA
Item number: Cay10008128-25
Protectin D1 (also known as neuroprotectin D1 when produced in neuronal tissues) is a DHA-derived dihydroxy fatty acid that exhibits potent protective and anti-inflammatory activities. 10(S),17(S)-DiHDHA is a DHA metabolite, also referred to as protectin DX (PDX). It is produced by an apparent double lipoxygenase...
| Keywords: | 10(S),17(S)-DiHDoHE, PDX, Protectin DX, 10(S),17(S)-dihydroxy-4Z,7Z,11E,13Z,15E,19Z-docosahexaenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 871826-47-0 |
| MW: | 360.5 D |
From 249.00€
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DMPC (1,2-Dimyristoyl-sn-glycero-3-phosphocholine) (14:0 PC)
Item number: IAX-700-400-5050
1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid utilized in liposomes and lipid bilayers for the study of biological membranes. Its utility extends to investigating the influence of lipids on enzymatic activity and protein function when formulated into nanodiscs, LNP or liposomes....
| Keywords: | 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (14:0 PC) |
| Application: | Synthetic phospholipid |
| CAS | 18194-24-6 |
| MW: | 677,9 D |
From 74.00€
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5(S)-HETE
Item number: Cay34230-25
5(S)-HETE is produced by the action of 5-LO on arachidonic acid to give 5(S)-HpETE, followed by reduction of the hydroperoxide. 5(S)-HETE has proliferative and chemotactic effects on granulocytes. When further metabolized to 5-oxoETE, it is a more potent eosinophil chemoattractant than leukotriene B4.Formal Name:...
| Keywords: | 5S-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 70608-72-9 |
| MW: | 320.5 D |
From 155.00€
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