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Item number: Cay90260-500
Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been found in human plasma, cell membranes, and adipose tissue. It contributes approximately 17% of the total fatty acids esterified to phosphatidylcholine, the major phospholipid class in porcine platelets. Oleic...
Keywords: | cis-9-Octadecenoic acid, 9Z-octadecenoic acid |
Application: | Bioactive lipid assays |
CAS | 112-80-1 |
MW: | 282.5 D |
From 29.00€
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Item number: Cay334570-25
12(S)-HETE-d8 is intended for use as an internal standard for the quantification of 12-HETE by GC- or LC-MS. (±)12-HETE is formed via non-enzymatic oxidation of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). 12(S)- and 12(R)-HETE are formed by 12(S)- and 12(R)-lipoxygenase-mediated oxidation of arachidonic...
Keywords: | 12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid |
Application: | Standard |
CAS | 84807-90-9 |
MW: | 328.5 D |
From 243.00€
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Item number: Cay34570-25
12(S)-HETE is the predominant lipoxygenase product of mammalian platelets. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.Formal Name: 12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid. CAS Number: 54397-83-0. Synonyms: 12(S)-Hydroxyeicosatetraenoic Acid....
Keywords: | 12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid |
Application: | Bioactive lipid assays |
CAS | 54397-83-0 |
MW: | 320.5 D |
From 193.00€
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Item number: Cay63150-5
Myriocin is an amino fatty acid antibiotic derived from certain thermophylic fungi, in this case Mycelia sterilia. It is a potent immunosuppressant having 10- to 100-fold more activity than cyclosporin A. Myriocin is a potent inhibitor of serine palmitoyltransferase (Ki = 0.28 nM), the enzyme that catalyzes the...
Keywords: | ISP-1, Thermozymocidin, 2S-amino-3R,4R-dihydroxy-2-(hydroxymethyl)-14-oxo-6E-eicosenoic acid |
Application: | Serine palmitoyltransferase inhibitor |
CAS | 35891-70-4 |
MW: | 401.5 D |
From 39.00€
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Item number: Cay10878-10
Maresin 1 is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids. It is produced from docosahexaenoic acid (DHA, Cay-90310, Cay-17950) in human peripheral blood mononuclear cells (PBMCs). Maresin 1 (100 nM) reduces TNF-alpha-induced increases in reactive oxygen species (ROS) in...
Keywords: | 7(R)-MaR1, 7(R)-Maresin 1, 7R,14S-dihydroxy-4Z,8E,10E,12Z,16Z,19Z-docosahexaenoic acid |
Application: | Inflammation studies |
CAS | 1268720-28-0 |
MW: | 360.5 D |
From 106.00€
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Item number: Cay90230-10
Dihomo-gamma-Linolenic Acid (DGLA, 20:3), an elongation product of gamma-linolenic acid (18:3), is rapidly metabolized by fatty acid desaturases to produce arachidonic acid (20:4). DGLA is metabolized through the cyclooxygenase pathway to produce 1-series prostaglandins, including PGE1. In mice, DGLA supplementation...
Keywords: | cis-8,11,14-Eicosatrienoic Acid, DGLA, gamma-Homolinolenic Acid, 8Z,11Z,14Z-eicosatrienoic acid |
Application: | LTB4 receptor antagonist |
CAS | 1783-84-2 |
MW: | 306.5 D |
From 47.00€
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Item number: Cay62215-5
1-Oleoyl-2-hydroxy-sn-glycero-3-PA is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of PLD or through a two step process involving liberation of DAG by PLC followed by phosphorylation of DAG by diglycerol kinase....
Keywords: | Oleoyl-sn-3-glycerophosphate, 9Z-octadecenoic acid, (2R)-2-hydroxy-3-(phosphonooxy)propyl ester, monosodium salt |
Application: | Bioactive lipid assays |
CAS | 325465-93-8 |
MW: | 458.5 D |
From 44.00€
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Item number: Cay10175-500
(±)-19(20)-EpDPA is an epoxide metabolite of docosahexaenoic acid (DHA, Cay-90310, Cay-17950). It is formed from DHA by various cytochrome P450 (CYP) isoforms. In vivo, (±)-19(20)-EpDPA (100 ng/animal, i.p.) suppresses hepatic crown-like structure (hCLS) formation and liver fibrosis in wild-type, but not...
Keywords: | (±)19,20 EDP, (±)19,20-EpDPE, (±)19,20-epoxy Docosapentaenoic Acid, (±)19,20-epoxy DPA,... |
Application: | CYP450 metabolism studies |
MW: | 344.5 D |
From 57.00€
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Item number: Cay90210-50
alpha-Linolenic acid (ALA) is an essential omega-3 polyunsaturated fatty acid found in plants. It is converted to the longer-chain fatty acids eicosapentaenoic (Cay-90110, Cay-90110.1, Cay-21908), docosapentaenoic (Cay-90165, Cay-21907), and docosahexaenoic acid (Cay-90310). It is also catabolized via fatty acid...
Keywords: | ALA, C18:3 (9Z,12Z,15Z), C18:3 n-3, 9Z,12Z,15Z-octadecatrienoic acid |
Application: | Bioactive lipid studies |
CAS | 463-40-1 |
MW: | 278.4 D |
From 36.00€
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Item number: Cay16390-100
8-iso-15-keto Prostaglandin F2alpha (8-iso-15-keto PGF2alpha) is a metabolite of the isoprostane 8-iso PGF2alpha in rabbits, monkeys, and humans. 8-isoprostane (8-iso PGF2alpha) is a prostaglandin-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-iso PGF2alpha is...
Keywords: | 8-epi-15-keto PGF2alpha, 8-iso-15-keto PGF2alpha, 9alpha,11alpha-dihydroxy-15-oxo-(8beta)-prosta-5Z,13E-dien-1-oic acid |
Application: | 8-iso PGF2alpha metabolite, vasoconstrictor |
CAS | 191919-01-4 |
MW: | 352.5 D |
From 44.00€
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Item number: Cay10006292-50
Fingolimod is an immune modulator, a prodrug form of the sphingosine-1-phosphate (S1P) receptor agonist FTY720 phosphate (Cay-10008639), and a derivative of myriocin (Cay-63150). It selectively inhibits calcium-dependent cytosolic phospholipase A2 (cPLA2) over calcium-independent PLA2 (iPLA2) and secretory PLA2...
Keywords: | FTY720, 2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol, hydrochloride |
Application: | Immune Modulator |
CAS | 162359-56-0 |
MW: | 343.9 D |
From 85.00€
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Item number: Cay10006627-10
Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively. Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid...
Keywords: | C16:0, hexadecanoic acid |
Application: | Bioactive lipid assays |
CAS | 57-10-3 |
MW: | 256.4 D |
From 44.00€
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