Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

Lipids are small,  organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids.... read more »
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Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

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Desacetylcinobufagin
Desacetylcinobufagin

Item number: Cay39822-1

Desacetylcinobufagin is an active metabolite of the cardiotonic steroid cinobufagin (Cay-19844). It is cytotoxic to HepG2, K562, and HL-60 cells (IC50s = 51.2, 50.1, and 7.5 µM, respectively).Formal Name: (5beta)-14,15beta-epoxy-3beta,16beta-dihydroxy-bufa-20,22-dienolide. CAS Number: 4026-95-3. Synonyms:...
Keywords: Deacetylcinobufagin, NSC 234203, (5beta)-14,15beta-epoxy-3beta,16beta-dihydroxy-bufa-20,22-dienolide
Application: Cardiotonic steroid cinobufagin active metabolite
CAS 4026-95-3
MW: 400.5 D
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15-deoxy-Delta12,14-Prostaglandin J2 serinol amide
15-deoxy-Delta12,14-Prostaglandin J2 serinol amide

Item number: Cay39917-1

15-deoxy-Delta12,14-Prostaglandin J2 serinol amide (15-deoxy-Delta12,14-PGJ2-SA) is a stable derivative of 15-deoxy-Delta12,14-PGJ2-2-glyceryl ester (Cay-10010132), which is a metabolite of PGD2 2-glyceryl ester.Formal Name:...
Keywords: 15-deoxy-Delta12,14-PGJ2-SA,...
Application: Stable 15-deoxy-Delta12,14-PGJ2-2-glyceryl ester derivative
MW: 389.5 D
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6beta-hydroxy Triamcinolone acetonide
6beta-hydroxy Triamcinolone acetonide

Item number: Cay40122-1

6beta-hydroxy Triamcinolone acetonide is a metabolite of the synthetic corticosteroid triamcinolone acetonide (Cay-18026). It is formed from triamcinolone acetonide by the cytochrome P450 (CYP) isoforms CYP3A4, CYP3A5, and CYP3A7. 6beta-hydroxy Triamcinolone acetonide has been found in wastewater effluent.Formal...
Keywords: 6beta-hydroxy TrA, 9-fluoro-6beta,11beta,21-trihydroxy-16alpha,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
Application: Triamcinolone acetonide metabolite
CAS 3869-32-7
MW: 450.5 D
650.00€ *
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Norbixin (hydrate)
Norbixin (hydrate)

Item number: Cay40132-1

Norbixin is a carotenoid that has been found in B. orellana and has diverse biological activities. It binds to peroxisome proliferator-activated receptor gamma (PPARgamma) in a cell-free assay (Ki = 1.15 µM). Norbixin (47.7 mg/kg) attenuates hyperglycemia, hyperinsulinemia, and insulin resistance, as well as...
Keywords: 4,8,13,17-tetramethyl-2E,4E,6E,8E,10E,12E,14E,16E,18E-eicosanonaenedioic acid, hydrate
Application: Bioactive carotenoid
MW: 380.5 D
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Biotin Sulfoxide
Biotin Sulfoxide

Item number: Cay40172-10

Biotin sulfoxide is a racemic mixture of the biotin (Cay-22582) metabolites biotin (R)-sulfoxide and biotin (S)-sulfoxide (Cay-34145).Formal Name: 5-((3aS,4S,6aR)-5-oxido-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid. CAS Number: 23015-53-4. Synonyms: (±)-Biotin Sulfoxide, D,L-Biotin Sulfoxide....
Keywords: (±)-Biotin Sulfoxide, D,L-Biotin Sulfoxide, 5-((3aS,4S,6aR)-5-oxido-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic...
Application: Racemic mixture, biotin metabolites
CAS 23015-53-4
MW: 260.3 D
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G0-C14 analog
G0-C14 analog

Item number: Cay40194-1

G0-C14 analog is a derivative of the ionizable cationic lipid G0-C14.Formal Name: 3,3',3'',3'''-(ethane-1,2-diylbis(azanetriyl))tetrakis(N-(2-(bis(2-hydroxytetradecyl)amino)ethyl)propanamide). CAS Number: 2935435-86-0. Molecular Formula: C134H272N10O12. Formula Weight: 2215.7. Purity: >95% (mixture of isomers)....
Keywords: 3,3',3'',3'''-(ethane-1,2-diylbis(azanetriyl))tetrakis(N-(2-(bis(2-hydroxytetradecyl)amino)ethyl)propanamide)
Application: Ionizable cationic lipid G0-C14 derivative
CAS 2935435-86-0
MW: 2215.7 D
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9322-O16B
9322-O16B

Item number: Cay40208-10

9322-O16B is an ionizable cationic lipid. It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro. LNPs containing 9322-O16B and encapsulating mRNA encoding chimeric antigen receptors (CARs) have been used in the generation of anti-CD19 CAR macrophages with anticancer...
Keywords: bis(2-(dodecyldisulfaneyl)ethyl) 3,3'-((3-(2-methyl-1H-imidazol-1-yl)propyl)azanediyl)dipropionate
Application: Ionizable cationic lipid, LNP formation
CAS 2909427-23-0
MW: 804.3 D
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IMCTA-C14 (trifluoroacetate salt)
IMCTA-C14 (trifluoroacetate salt)

Item number: Cay40230-5

IMCTA-C14 is a detergent and derivative of the microbial metabolite 4-trehalosamine (Cay-40229). It has a critical micelle concentration (CMC) of 0.11 mM and a hydrophilic-lipophilic balance (HLB) value of 9.72. IMCTA-C14 (0.05 and 0.5%) extracts proteins, including membrane proteins, from OVK18 ovarian cancer...
Keywords: (2R,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6S)-3,4-dihydroxy-6-(hydroxymethyl)-5-(tetradecylamino)tetrahydro-2H-pyran-2-yl)oxy)-6-(...
Application: 4-trehalosamine derivative, detergent
MW: 651.7 D
582.00€ *
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Ouabain (hydrate)
Ouabain (hydrate)

Item number: Cay14319-1

Ouabain is a cardiac glycoside that has been found in S. gratus and has diverse biological activities. It inhibits the Na+/K+-ATPase isoforms alpha1beta1 and alpha2beta1 and human-ether-a-go-go (hERG), also known as Kv11.1 (IC50s = 97, 90, and 15.2 nM, respectively). Ouabain reduces the proliferation of PC3 prostate...
Keywords: g-Strophanthin, 3beta-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-1beta,5beta,11alpha,14,19-pentahydroxy-card-20(22)-enolide,...
Application: Bioactive cardiac glycoside
CAS 340169-01-9
MW: 584.7 D
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1-O-Dodecyl-rac-glycerol
1-O-Dodecyl-rac-glycerol

Item number: Cay17441-1

1-O-Dodecyl-rac-glycerol is an alkyl glyceryl ether. It is also a nonionic surfactant. 1-O-Dodecyl-rac-glycerol increases autolysin activity in S. faecium and inhibits peptidoglycan synthesis in S. mutans. It induces mouse peritoneal macrophage activation ex vivo when administered at a dose of 100 ng/animal....
Keywords: 1-O-Lauryl-rac-glycerol, 2,3-Dihydroxypropyl dodecyl ether, DDG, Lauryl glyceryl ether, MG(O-12:0/0:0/0:0), NSC 38645,...
Application: Alkyl glyceryl ether, nonionic surfactant
CAS 1561-07-5
MW: 260.4 D
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12-keto Chenodeoxycholic Acid
12-keto Chenodeoxycholic Acid

Item number: Cay30838-1

12-keto Chenodeoxycholic acid (12-keto CDCA) is an intermediate in the semisynthetic synthesis of ursodeoxycholic acid (Cay-31016, Cay-15121) and chenodeoxycholic acid (Cay-10011286, Cay-35346) from the primary bile acid cholic acid (Cay-20250). 12-keto CDCA has been found in the gastric tissues of C57BL/6J mice, KM...
Keywords: 12-keto CDCA, 12-oxo CDCA, 12-oxo Chenodeoxycholic Acid, 3alpha,7alpha-Dihydroxy-12-keto-5beta-cholanic acid,...
Application: Ursodeoxycholic acid / chenodeoxycholic acid synthesis intermediate
CAS 2458-08-4
MW: 406.6 D
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Acetyl-DL-carnitine (chloride)
Acetyl-DL-carnitine (chloride)

Item number: Cay31015-100

Acetyl-DL-carnitine is a racemic mixture of the short-chain acylcarnitine acetyl-D-carnitine and the mitochondrial metabolite acetyl-L-carnitine (Cay-16948). It increases the oxidation rate of the branched-chain 2-oxo acid 3-methyl-2-butanoate in isolated rat muscle mitochondria in the absence of carnitine when used...
Keywords: (±)-Acetylcarnitine, C2:0 Carnitine, CAR 2:0, DL-Acetylcarnitine, DL-Carnitine acetyl ester,...
Application: Acetyl-D-carnitine / acetyl-L-carnitine racemic mixture
CAS 2504-11-2
MW: 239.7 D
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315 from 320 pages