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Chonglou Saponin VII
Item number: Cay39251-1
Chonglou saponin VII is a steroid saponin that has been found in P. polyphylla and has anticancer activities. It inhibits the proliferation of HepG2 cells and HepG2 cells resistant to doxorubicin (HepG2/ADR cells) when used at concentrations of 1.98 and 2.97 µM. Chonglou saponin VII (1.98 µM) reduces ADR resistance...
| Keywords: | Paris Saponin VII, PS VII, (3beta,25R)-17-hydroxyspirost-5-en-3-yl... |
| Application: | Steroid saponin, anticancer agent |
| CAS | 68124-04-9 |
| MW: | 1031.2 D |
From 133.00€
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Cardiolipin (14:1/14:1/14:1/14:1) (sodium salt)
Item number: Cay39280-1
Cardiolipin (14:1/14:1/14:1/14:1) is an anionic phospholipid containing the monounsaturated fatty acid myristoleic acid (Cay-9002461).Formal Name: (9Z,9'Z,9''Z,9'''Z)-9-Tetradecenoic acid, 1,1',1'',1'''-[(2R,14R)-5,8,11-trihydroxy-5,11-dioxido-4,6,10,12-tetraoxa-5,11-diophosphapentadecane-1,2,14,15-tetrayl] ester,...
| Keywords: | 14:1 Cardiolipin, Tetramyristoleoyl Cardiolipin, (9Z,9'Z,9''Z,9'''Z)-9-Tetradecenoic acid,... |
| Application: | Phospholipid |
| CAS | 2260669-33-6 |
| MW: | 1277.6 D |
45.00€
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244cis
Item number: Cay39284-10
244cis is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs). LNPs containing 244cis and encapsulating an mRNA reporter specifically accumulate in the lungs and induce lower serum chemokine (C-C motif) ligand 2 (CCL2) levels than LNPs containing SM-102 (Cay-33474) in mice....
| Keywords: | di((Z)-non-2-en-1-yl) 9,9'-((2-(4-(9-(((Z)-non-2-en-1-yl)oxy)-9-oxononyl)piperazin-1-yl)ethyl)azanediyl)dinonanoate |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 970.6 D |
From 125.00€
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Cholesterol (plant)
Item number: Cay39448-1
Cholesterol is a minor sterol produced in plant cells and a component of plant surface lipids. Cholesterol content in plants is generally several hundreds- to thousands-fold less than that of mammalian cells. It is a precursor in the synthesis of various bioactive plant metabolites, including steroidal...
| Keywords: | NSC 8798, Provitamin D, (3beta)-cholest-5-en-3-ol |
| Application: | Minor plant sterol |
| CAS | 57-88-5 |
| MW: | 386.7 D |
From 100.00€
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SM-102 N-oxide
Item number: Cay39636-1
SM-102 N-oxide is potential impurity in commercial preparations of SM-102.Formal Name: 8-(heptadecan-9-yloxy)-N-(2-hydroxyethyl)-8-oxo-N-(6-oxo-6-(undecyloxy)hexyl)octan-1-amine oxide. CAS Number: 2824195-50-6. Synonyms: CAY10779 N-oxide, Lipid H N-oxide, LNP-102 N-oxide. Molecular Formula: C44H87NO6. Formula...
| Keywords: | CAY10779 N-oxide, Lipid H N-oxide, LNP-102 N-oxide,... |
| Application: | Commercial SM-102 preparation potential impurity |
| CAS | 2824195-50-6 |
| MW: | 726.2 D |
From 48.00€
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10-Chloroestra-1,4-diene-3,17-dione
Item number: Cay39758-1
10-Chloroestra-1,4-diene-3,17-dione is a sterone agonist of estrogen receptor alpha (ERalpha). It increases reporter gene expression in S. cerevisiae (EC50 = 0.36 nM for the human receptor). It also is an aromatase inhibitor (IC50 = 2.4 µM).Formal Name: 10-chloro-estra-1,4-diene-3,17-dione. CAS Number: 91413-55-7....
| Keywords: | 10-chloro-1,4-Estradiene, 10-chloro-estra-1,4-diene-3,17-dione |
| Application: | Sterone ERalpha agonist |
| CAS | 91413-55-7 |
| MW: | 304.8 D |
From 41.00€
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ALC-0315 N-oxide
Item number: Cay39797-1
ALC-0315 N-oxide is a potential impurity in commercial preparations of the ionizable cationic amino lipid ALC-0315.Formal Name: 6-((2-hexyldecanoyl)oxy)-N-(6-((2-hexyldecanoyl)oxy)hexyl)-N-(4-hydroxybutyl)hexan-1-amine oxide. Molecular Formula: C48H95NO6. Formula Weight: 782.3. Purity: >98%. Formulation: (Request...
| Keywords: | 6-((2-hexyldecanoyl)oxy)-N-(6-((2-hexyldecanoyl)oxy)hexyl)-N-(4-hydroxybutyl)hexan-1-amine oxide |
| Application: | Commercial ALC-0315 preparation potential impurity |
| MW: | 782.3 D |
From 49.00€
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S-Geranylgeranyl-L-glutathione
Item number: Cay9004116-1
S-Geranylgeranyl-L-glutathione is a ligand of the orphan G protein-coupled receptor (GPCR) P2RY8. It selectively induces internalization of P2RY8 over sphingosine-1-phosphate receptor 2 (S1P2), GPR55, cysteinyl leukotriene receptor 1 (CysLT1 receptor), and CysLT2 receptor at 100 nM. S-Geranylgeranyl-L-glutathione...
| Keywords: | GGG,... |
| Application: | P2RY8 ligand |
| CAS | 2364639-42-7 |
| MW: | 579.8 D |
From 35.00€
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DLin-MC4-DMA
Item number: Cay39732-10
DLin-MC4-DMA is an ionizable cationic lipid (pKa = 6.93). Lipid nanoparticles (LNPs) containing DLin-MC4-DMA and encapsulating siRNA for the gene encoding mouse coagulation factor VII (F7) reduce its gene expression levels in mice.Formal Name: 5-(dimethylamino)-pentanoic acid,...
| Keywords: | MC4, 5-(dimethylamino)-pentanoic acid, (10Z,13Z)-1-(9Z,12Z)-9,12-octadecadien-1-yl-10,13-nonadecadien-1-yl ester |
| Application: | Ionizable cationic lipid |
| CAS | 1226909-66-5 |
| MW: | 656.1 D |
From 193.00€
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Colneleic Acid
Item number: Cay10005076-100
Colneleic acid is a divinyl ether oxylipin and an active metabolite of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) that has been found in potatoes. It is formed from linoleic acid by 9-lipoxygenase (9-LO) via a (±)9-HpODE (Cay-10705) intermediate and divinyl ether synthase. Colneleic acid decreases P....
| Keywords: | FA 18:3,O, 9-[(1E,3Z)-1,3-nonadien-1-yloxy]-8E-nonenoic acid |
| Application: | Oxylipin |
| CAS | 52761-34-9 |
| MW: | 294.4 D |
472.00€
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Pinolenic Acid ethyl ester
Item number: Cay10008658-1
Pinolenic acid is a polyunsaturated fatty acid found in Korean pine (Pinus orientalis) and maritime pine (Pinus pinaster) seed oils. Both oils have been found to have lipid-lowering properties. A diet containing maritime pine seed oil (MPSO) lowered high-density lipoprotein and ApoA1 levels in transgenic mice...
| Keywords: | 5Z,9Z,12Z-octadecatrienoic acid, ethyl ester |
| Application: | Bioactive lipid assays |
| CAS | 493015-74-0 |
| MW: | 306.5 D |
From 28.00€
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TK05
Item number: Cay19793-1
TK05 is an inhibitor of leukotriene C4 (LTC4) synthase (IC50 = 95 nM). It is selective for LTC4 synthase over microsomal prostaglandin E synthase-1 (mPGES-1), microsomal glutathione S-transferase 2 (GST2), and 5-lipoxygenase (5-LO) at 10 µM. TK05 (1 µM) inhibits LTC4 synthase in Mono-Mac-6 leukemia cells and...
| Keywords: | 5-[[5-[(4-chlorophenyl)(cyclopropylmethyl)amino]-2-pyridinyl]carbonyl]-2-(4-methoxybenzoyl)-benzoic acid |
| Application: | LTC4 synthase inhibitor |
| CAS | 1245734-61-5 |
| MW: | 541 D |
From 153.00€
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