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5(S)-HpETE
Item number: Cay44230-25
5(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 5-LO on arachidonic acid. It is metabolized to leukotriene A4 (LTA4), a key intermediate in the formation of LTs. 5(S)-HpETE (1 µM) mediates the induction of the proto-oncogene c-fos in TNF-stimulated TA1 cells.Formal Name:...
| Keywords: | 5S-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 71774-08-8 |
| MW: | 336.5 D |
From 146.00€
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(±)11(12)-DiHET
Item number: Cay51511-25
Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. (±)11(12)-DiHET relaxes U-46619 (Cay-16450)-contracted artery rings with approximately 70% of the magnitude of (±)11(12)-EET (Cay-50511).Formal Name: (±)11,12-dihydroxy-5Z,8Z,14Z-eicosatrienoic...
| Keywords: | (±)11,12-DiHETrE, (±)11,12-dihydroxy-5Z,8Z,14Z-eicosatrienoic acid |
| Application: | Bioactive lipid studies |
| MW: | 338.5 D |
From 133.00€
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gamma-Linolenic Acid
Item number: Cay90220-50
gamma-Linolenic acid (GLA) is an omega-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak LTB4 receptor antagonist, inhibiting [3H]-LTB4 binding to porcine neutrophil membranes with a Ki of 1 µM. GLA produces 53% inhibition at a 1 mg/kg dose in an in vivo model...
| Keywords: | GLA, 6Z,9Z,12Z-octadecatrienoic acid |
| Application: | LTB4 receptor antagonist |
| CAS | 506-26-3 |
| MW: | 278.4 D |
From 35.00€
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Arachidonic Acid (sodium salt)
Item number: Cay10006607-100
Polyunsaturated fatty acids (PUFAs) are essential nutrients that show distinct deficiency syndromes when not present in adequate amounts in the diet. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free...
| Keywords: | Sodium Arachidonate, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, monosodium salt |
| Application: | Bioactive lipid assays |
| CAS | 6610-25-9 |
| MW: | 326.5 D |
From 69.00€
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Docosahexaenoic Acid-d5
Item number: Cay10005057-50
Docosahexaenoic acid-d5 (DHA-d5) is intended for use as an internal standard for the quantification of DHA (Cay-90310) by GC- or LC-MS. DHA is a long-chain omega-3 polyunsaturated fatty acid (PUFA) found in fish and algal oils. It comprises approximately 40% of total brain PUFAs and is abundant in grey matter and...
| Keywords: | Cervonic Acid-d5, DHA-d5, 4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic-21,21,22,22,22-d5 acid |
| Application: | Standard |
| CAS | 1197205-71-2 |
| MW: | 333.5 D |
From 94.00€
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Docosahexaenoyl Ethanolamide
Item number: Cay10007534-5
Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant omega-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for...
| Keywords: | DEA, DHEA, Synaptamide, N-(2-hydroxyethyl)-4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenamide |
| Application: | Bioactive lipid assays |
| CAS | 162758-94-3 |
| MW: | 371.6 D |
From 48.00€
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1-Oleoyl-2-hydroxy-sn-glycero-3-PA
Item number: Cay10010093-5
1-Oleoyl-2-hydroxy-sn-glycero-3-PA (1-Oleoyl LPA) is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by...
| Keywords: | 1-Oleoyl LPA, Oleoyl-sn-3-Glycerophosphate, 1-O-9Z-octadecenoyl-sn-glyceryl-3-phosphoric acid |
| Application: | Bioactive lipid assays |
| CAS | 65528-98-5 |
| MW: | 436.5 D |
From 36.00€
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C16 Ceramide (d18:1/16:0)
Item number: Cay10681-1
C16 Ceramide is a sphingolipid. It incorporates into the mitochondrial outer membrane and forms channels that increase its permeability. C16 Ceramide levels are increased by PPMP or MAPP in isolated human neutrophils and are correlated with an increase in apoptosis. It accumulates in the lungs of patients with...
| Keywords: | Cer(d18:1/16:0), Ceramide (d18:1/16:0), N-Palmitoyl-D-erythro-Sphingosine, Palmitoyl Ceramide,... |
| Application: | Bioactive lipid assays |
| CAS | 24696-26-2 |
| MW: | 537.9 D |
From 31.00€
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(±)5(6)-DiHET
Item number: Cay51211-25
5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET (Cay-50211, Cay-10007260) by epoxide hydrolases. 5(6)-DiHET can be used to quantify 5(6)-EET due to the conversion of 5(6)-EET to 5(6)-delta-lactone in solution. 5(6)-DiHET activates large-conductance calcium-activated...
| Keywords: | (±)5,6-DiHETrE, (±)5,6-dihydroxy-8Z,11Z,14Z-eicosatrienoic acid |
| Application: | Bioactive lipid assays |
| CAS | 213382-49-1 |
| MW: | 338.5 D |
From 126.00€
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Resolvin D2-d5
Item number: Cay11184-10
Resolvin D2-d5 (RvD2-d5) is intended for use as an internal standard for the quantification of resolvin D2 (Cay-10007279) by GC- or LC-MS. Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). In addition to being anti-inflammatory, resolvins...
| Keywords: | 7(S),16(R),17(S)-Resolvin D2-d5, RvD2-d5, 7S,16R,17S-trihydroxy-4Z,8E,10Z,12E,14E,19Z-21,21',22,22,22-d5 docosahexaenoic acid |
| Application: | Standard, bioactive lipid assays |
| CAS | 1881277-33-3 |
| MW: | 381.5 D |
From 231.00€
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(±)12-HETE
Item number: Cay34550-25
(±)12-HETE is a racemic mixture of the arachidonic acid metabolites 12(R)-HETE (Cay-34560) and 12(S)-HETE (Cay-34570). It is formed via non-enzymatic oxidation of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). 12(S)- and 12(R)-HETE are formed by 12S- and 12R-lipoxygenase-mediated oxidation of arachidonic...
| Keywords: | (±)12-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid studies |
| CAS | 71030-37-0 |
| MW: | 320.5 D |
From 99.00€
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(±)19(20)-DiHDPA
Item number: Cay10007001-50
Docosahexaenoic acid (DHA, Cay-90310) is an essential fatty acid and the most abundant omega-3 fatty acid in neural tissues, especially in the retina and brain. (±)19(20)-DiHDPA is one of the major metabolites produced when DHA is incubated with NADPH-supplemented rat liver microsomes. DHA is also slowly metabolized...
| Keywords: | (±)19,20-DiHDoPE, (±)19,20-dihydroxy-4Z,7Z,10Z,13Z,16Z-docosapentaenoic acid |
| Application: | Bioactive lipid assays |
| MW: | 362.5 D |
From 116.00€
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