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(±)12(13)-EpOME
Item number: Cay52450-250
(±)12(13)-EpOME is the 12,13-cis epoxide form of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909). It is formed primarily via linoleic acid metabolism by the cytochrome P450 (CYP) isoforms CYP2J2, CYP2C8, and CYP2C9, however, CYP1A1 can contribute to (±)12(13)-EpOME production when pharmacologically induced....
| Keywords: | (±)12,13-EODE, (±)-Vernolic Acid, Isoleukotoxin, (±)12(13)epoxy-9Z-octadecenoic acid |
| Application: | Bioactive lipid studies |
| MW: | 296.5 D |
From 53.00€
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C8 Ceramide (d18:1/8:0)
Item number: Cay62540-1
C8 Ceramide (d18:1/8:0) is a cell-permeable analog of naturally occurring ceramides. Unlike C2 ceramide, it is metabolized within cells to generate natural ceramides, often causing a dramatic increase in cellular ceramide levels. For this reason, treatment of cells with C8 Ceramide (d18:1/8:0) may more closely mimic...
| Keywords: | C8 Ceramide, Cer(d18:1/8:0), N-Octanoylsphingosine, N-octanoyl-D-erythro-Sphingosine,... |
| Application: | Bioactive lipid assays |
| CAS | 74713-59-0 |
| MW: | 425.7 D |
From 31.00€
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H1L1A1B3
Item number: Cay41199-5
H1L1A1B3 is an ionizable cationic lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of circular RNA (circRNA) in vitro and in vivo. LNPs containing H1L1A1B3 and encapsulating circRNA encoding IL-12 induce IL-12 production four times more...
| Keywords: | 7-(cyclohexylamino)-6-(N-(3-(dimethylamino)propyl)-4-methylnonanamido)-7-oxoheptyl dodecanoate |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 664.1 D |
From 136.00€
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DSPE-PEG(2000) Maleimide
Item number: Cay42013-10
DSPE-PEG(2000) maleimide is a PEGylated derivative of 1,2-distearoyl-rac-3-PE (DSPE). It has been used in the synthesis of lipid nanoparticles (LNPs) for the delivery of siRNA or small molecule anticancer agents in vitro and in vivo. LNPs containing DSPE-PEG(2000) maleimide and encapsulating siRNAs targeting mRNA...
| Keywords: | 1,2-Distearoyl-rac-glycero-3-Phosphoethanolamine-PEG-2000 Maleimide,... |
| Application: | PEGylated DSPE derivative, LNP formation |
| CAS | 185844-12-6 |
From 134.00€
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15(R)-15-methyl Prostaglandin D2
Item number: Cay12720-1
15(R)-15-methyl Prostaglandin D2 (15(R)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2 (Cay-12010). The physiological actions of PGD2 include regulation of sleep, lowering of body temperature, inhibition of platelet aggregation and relaxation of vascular smooth muscle. PGD2 mediates its effects...
| Keywords: | 15(R)-15-methyl PGD2, 9alpha,15R-dihydroxy-11-oxo-15-methyl-prosta-5Z,13E-dien-1-oic acid |
| Application: | CRTH2 receptor agonist, DP2 receptor agonist |
| CAS | 210978-26-0 |
| MW: | 366.5 D |
From 48.00€
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Ganglioside GM1 . sodium salt (bovine brain)
Item number: AG-CN2-9000-M001
Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell...
| Keywords: | GM1 . Na, Monosialoganglioside GM1 . Na |
| Application: | Acidic glycosphingolipid |
| CAS | 37758-47-7 |
| MW: | 1545,8 D |
From 99.00€
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1,2,3-Triheptadecanoyl Glycerol
Item number: Cay16489-1
1,2,3-Triheptadecanoyl glycerol is a triacylglycerol that contains heptadecanoic acid (Cay-19722) at the sn-1, sn-2, and sn-3 positions.Formal Name: heptadecanoic acid, 1,1',1''-(1,2,3-propanetriyl) ester. CAS Number: 2438-40-6. Synonyms: Glycerol Triheptadecanoate, TG(17:0/17:0/17:0). Molecular Formula: C54H104O6....
| Keywords: | Glycerol Triheptadecanoate, TG(17:0/17:0/17:0), heptadecanoic acid, 1,1',1''-(1,2,3-propanetriyl) ester |
| Application: | Saturated triacylglycerol |
| CAS | 2438-40-6 |
| MW: | 849.4 D |
From 44.00€
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(±)5-HETE
Item number: Cay34210-25
(±)5-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. It contains equal amounts of 5(S)-HETE and 5(R)-HETE. (±)5-HETE induces the aggregation of isolated neutrophils with an IC50 value of 200 nM.Formal Name: (±)5-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid....
| Keywords: | (±)5-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid studies |
| CAS | 73307-52-5 |
| MW: | 320.5 D |
From 99.00€
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C9-200
Item number: Cay40862-1
C9-200 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNPs). LNPs containing C9-200 and encapsulating mRNA encoding erythropoietin (EPO) increase serum EPO levels in mice. LNPs containing C9-200 and encapsulating mRNA encoding the Cas9 nuclease and small-guide RNA (sgRNA)...
| Keywords: | 1,1'-((2-(4-(2-((2-(bis(2-hydroxynonyl)amino)ethyl)(2-hydroxynonyl)amino)ethyl)piperazin-1-yl)ethyl)azanediyl)bis(nonan-2-ol) |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 926.5 D |
From 40.00€
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Lipid N2-3L
Item number: Cay40911-1
Lipid N2-3L is an ionizable cationic lipid (pKa = 8.99) that has been used in the generation of supramolecular lipid nanoparticles (SMLNPs) encapsulating mRNA for use in vitro and in vivo. SMLNPs containing lipid N2-3L and encapsulating a luciferase reporter accumulate at the site of injection and in the draining...
| Keywords: | 9Z-octadecenoic acid,... |
| Application: | Ionizable cationic lipid, SMLNP generation |
| CAS | 2924606-55-1 |
| MW: | 840.3 D |
From 103.00€
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N-Lithocholyl-L-Leucine
Item number: Cay40931-1
N-Lithocholyl-L-leucine is a bile acid conjugate composed of lithocholic acid (Cay-20253) and L-leucine (Cay-34342). It has been used in the formation of hydrogels.Formal Name: N-[(3alpha,5beta)-3-hydroxy-24-oxocholan-24-yl]-L-leucine. CAS Number: 2095154-73-5. Molecular Formula: C30H51NO4. Formula Weight: 489.7....
| Keywords: | N-[(3alpha,5beta)-3-hydroxy-24-oxocholan-24-yl]-L-leucine |
| Application: | Bile acid conjugate, hydrogel formation |
| CAS | 2095154-73-5 |
| MW: | 489.7 D |
From 54.00€
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Q1-ALC-0315 (iodide)
Item number: Cay41240-1
Q1-ALC-0315 is a cationic quaternary ammonium lipid derivative of the ionizable cationic lipid ALC-0315 (Cay-34337) that has been used in the generation of lipid nanoparticles (LNPs) for use in vivo. LNPs containing Q1-ALC-0315 and ALC-0315 as a cationic lipid pair (CLP) and encapsulating mRNA encoding a luciferase...
| Keywords: | 6-((2-hexyldecanoyl)oxy)-N-(6-((2-hexyldecanoyl)oxy)hexyl)-N-(4-hydroxybutyl)-N-methylhexan-1-aminium, monoiodide |
| Application: | Ionizable cationic lipid ALC-0315 cationic quaternary ammonium lipid derivative, LNP formation |
| MW: | 908.2 D |
From 40.00€
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