No results were found for the filter!
Oleoyl Ethanolamide
Item number: Cay90265-100
Oleoyl ethanolamide (OEA) is an analog of the endocannabinoid AEA found in brain tissue and in chocolate. It is one of the long chain fatty acid ethanolamides that accumulates rapidly in infarcted tissue, but its biosynthesis is reduced in the intestine of rats following food deprivation. OEA is an endogenous,...
| Keywords: | OEA, Oleic Acid Ethanolamide, N-(2-hydroxyethyl)-9Z-octadecenamide |
| Application: | AEA analog |
| CAS | 111-58-0 |
| MW: | 325.5 D |
From 35.00€
*
Pentacosanoic Acid methyl ester
Item number: Cay10006451-100
Long chain saturated fatty acids and their esters are common components of plant lipids. Pentacosanoic acid methyl ester is the methyl ester of the 25-carbon, fully saturated fatty acid pentacosanoic acid. This product is designed to be used as a standard in total fatty acid analysis.Formal Name: pentacosanoic acid,...
| Keywords: | Methyl Pentacosanoate, pentacosanoic acid, methyl ester |
| Application: | Standard |
| CAS | 55373-89-2 |
| MW: | 396.7 D |
From 91.00€
*
JTE-013
Item number: Cay10009458-10
JTE-013 is a sphingosine-1-phosphate receptor 2 (S1P2) and S1P4 antagonist (IC50s = 17 and 237 nM, respectively). It is selective for S1P2 over S1P1 and S1P3 (IC50s = >10 µM for both). JTE-013 (1 and 10 µM) reverses S1P-induced inhibition of human umbilical vein endothelial cell (HUVEC) and smooth muscle cell (SMC)...
| Keywords: | N-(2,6-dichloro-4-pyridinyl)-2-[1,3-dimethyl-4-(1-methylethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]-hydrazinecarboxamide |
| Application: | S1P2 receptor antagonist |
| CAS | 383150-41-2 |
| MW: | 408.3 D |
From 36.00€
*
15(S)-HETE
Item number: Cay34720-25
15(S)-HETE is an active metabolite of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). It is formed via oxidation of arachidonic acid by 15-lipoxygenase 2 (15-LO-2) in macrophages, as well as the prostate, lung, and skin, but also by 15-LO-1 in airway epithelial cells, eosinophils, and reticulocytes....
| Keywords: | 15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 54845-95-3 |
| MW: | 320.5 D |
From 54.00€
*
(±)17(18)-EpETE
Item number: Cay50861-500
(±)17(18)-EpETE is biosynthesized by the stereospecific epoxidation of the omega-3 bond of EPA. (±)17(18)-EpETE at 100 nM was found to be a potent and selective activator of large-conductance calcium-activated potassium channels (KCa1.1/BK) in vascular smooth muscle cells. It is possible that some of the physiologic...
| Keywords: | (±)17,18-EEQ, (±)17,18-epoxy Eicosatetraenoic Acid, (±)17,18-epoxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| MW: | 318.5 D |
From 78.00€
*
DMG-PEG(2000)
Item number: Cay33945-500
DMG-PEG(2000) is a lipid excipient that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Administration of fumarylacetoacetate hydrolase (FAH) mRNA in DMG-PEG(2000)-containing LNPs increases survival in a mouse model of hereditary tyrosinemia type 1 (HT-1). Formulations...
| Keywords: | 1,2-Dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000,... |
| Application: | Lipid excipient |
| CAS | 160743-62-4 |
From 184.00€
*
C12-200
Item number: Cay36699-50
C12-200 is a branched-chain ionizable cationic lipidoid. It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA, siRNA, or self-amplifying RNA (saRNA). Administration of human erythropoietin (EPO) mRNA or factor VII siRNA in C12-200-containing LNPs...
| Keywords: | 1,1'-[[2-[4-[2-[[2-[bis(2-hydroxydodecyl)amino]ethyl](2-hydroxydodecyl)amino]ethyl]-1-piperazinyl]ethyl]imino]bis-2-dodecanol |
| Application: | Branched-chain ionizable lipidoid |
| CAS | 1220890-25-4 |
| MW: | 1136.9 D |
From 144.00€
*
2-Arachidonoyl Glycerol-d8
Item number: Cay362160-100
2-Arachidonoyl glycerol-d8 (2-AG-d8) is intended for use as an internal standard for the quantification of 2-AG (Cay-62160) by GC- or LC-MS. 2-AG is an endogenous agonist of the CB1 receptor. Unlike anandamide, 2-AG is present at relatively high levels in the central nervous system, it is the most abundant molecular...
| Keywords: | 2-AG-d8, 5Z,8Z,11Z,14Z-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid, 2-glyceryl ester |
| Application: | Standard |
| CAS | 924894-97-3 |
| MW: | 386.6 D |
From 103.00€
*
Palmitoleic Acid
Item number: Cay10009871-100
Palmitoleic acid is an omega-7 monounsaturated fatty acid that has been found in macadamia and sea buckthorn oils. It increases basal and insulin-stimulated glucose uptake and glucose transporter 4 (Glut4) protein levels in 3T3-L1 adipocytes when used at a concentration of 200 µM. Ex vivo, palmitoleic acid (300...
| Keywords: | (9Z)-Hexadecenoic Acid, cis-Palmitoleic Acid, C16:1 n-7, C16:1(9Z), (9Z)-hexadecenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 373-49-9 |
| MW: | 254.4 D |
From 35.00€
*
1-Arachidonoyl Glycerol
Item number: Cay62150-1
The glyceryl esters of arachidonic acid have been proposed as endogenous cannabinoid ligands. 2-AG is 10 to 100 times more potent than 1-AG in ligand binding affinity and agonist activity at the CB1 receptor, and is thus considered to be the natural ligand. However, 2-AG is chemically unstable and undergoes rapid...
| Keywords: | 1-AG, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 1-glyceryl ester |
| Application: | CB1 receptor agonist |
| CAS | 35474-99-8 |
| MW: | 378.6 D |
From 35.00€
*
Palmitic Acid Alkyne
Item number: Cay13266-1
Protein S-palmitoylation is the post-translational acylation of proteins and serves to regulate localization, stability, and interaction with associates and substrates. Palmitic acid alkyne is a form of palmitic acid (Cay-10006627) with an omega-terminal alkyne. The terminal alkyne group can be used in linking...
| Keywords: | Alk-14, Click Tag(TM) Palmitic Acid Alkyne, 15-hexadecynoic acid |
| Application: | Lipid bioconjugation |
| CAS | 99208-90-9 |
| MW: | 252.4 D |
From 87.00€
*
Arachidonoyl Ethanolamide-d8
Item number: Cay390050-100
Arachidonoyl ethanolamide-d8 (AEA-8) contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of AEA by GC- or LC-mass spectrometry. AEA is the ethanolamine amide of arachidonic acid, first isolated from porcine brain. It is...
| Keywords: | AEA-d8, Anandamide-d8, N-(2-hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide-5,6,8,9,11,12,14,15-d8 |
| Application: | Standard |
| CAS | 924894-98-4 |
| MW: | 355.6 D |
From 67.00€
*