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Lauroylsarcosine (sodium salt)
Item number: Cay33718-100
Lauroylsarcosine is a fatty acid amide and detergent. It has been used to solubilize recombinant and membrane proteins.Formal Name: N-methyl-N-(1-oxododecyl)-glycine, monosodium salt. CAS Number: 137-16-6. Synonyms: Sarkosyl, SDDS, Sodium Lauroyl Sarcosinate, Sodium N-dodecanoyl Sarcosinate. Molecular Formula:...
| Keywords: | Sarkosyl, SDDS, Sodium Lauroyl Sarcosinate, Sodium N-dodecanoyl Sarcosinate, N-methyl-N-(1-oxododecyl)-glycine, monosodium... |
| Application: | Fatty acid amide, detergent |
| CAS | 137-16-6 |
| MW: | 293.4 D |
From 52.00€
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NEW
1-Octadecyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt)
Item number: Cay10010291-10
1-Oleyl-2-hydroxy-sn-glycero-3-PA (1-Octadecyl LPA) is a LPA analog containing stearyl alcohol at the sn-1 position. LPA binds to one of five different G protein-linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite...
| Keywords: | 1-Octadecyl LPA, 1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate, monosodium salt |
| Application: | Lysophosphatidic (LPA) analog |
| MW: | 446.5 D |
442.00€
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DOG-IM4
Item number: Cay37441-1
DOG-IM4 is an ionizable cationic lipid (apparent pKa = 5.6) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA. Immunization with LNPs containing DOG-IM4 and encapsulating mRNA encoding influenza A hemagglutinin (HA) increases HA-inhibiting antibody titers (HI titers) in mice...
| Keywords: | N-[(25Z)-14-[(9Z)-9-octadecen-1-yloxy]-3,6,9,12,16-pentaoxatetratriacont-25-en-1-yl]-1H-imidazole-5-carboxamide |
| Application: | Ionizable cationic lipid, LNP formation, mRNA delivery |
| CAS | 2758097-38-8 |
| MW: | 862.3 D |
From 84.00€
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306-O12B
Item number: Cay37549-10
306-O12B is an ionizable cationic lipidoid. It has been used in the generation of lipid nanoparticles (LNPs). Intravenous administration of LNPs containing 306-O12B and encapsulating an mRNA reporter accumulate specifically in the mouse liver. LNPs containing 306-O12B and encapsulating mRNA encoding the Cas9...
| Keywords: | tetrakis(2-(octyldisulfaneyl)ethyl) 3,3',3'',3'''-(((methylazanediyl)bis(propane-3,1-diyl))bis(azanetriyl))tetrapropionate |
| Application: | Ionizable cationic lipidoid, LNP formation |
| CAS | 2566523-06-4 |
| MW: | 1251.1 D |
From 144.00€
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IR-117-17
Item number: Cay40420-10
IR-117-17 is an ionizable cationic and biodegradable amino lipid. It has been used in the generation of lipid nanoparticles (LNPs). Nebulized administration of LNPs containing IR-117-17 and the cationic lipid 1,2-dioleoyl-2-trimethylammoniumpropane (1,2-DOTAP, Cay-15110), among other components, and encapsulating...
| Keywords: | A10-LIN, 5-(((3-(dibutylamino)propyl)amino)methyl)-6-hydroxyundecane-1,11-diyl (9Z,9'Z,12Z,12'Z)-bis(octadeca-9,12-dienoate) |
| Application: | Ionizable cationic, biodegradable amino lipid, LNP formation |
| CAS | 2940241-38-1 |
| MW: | 927.5 D |
From 473.00€
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15(S)-HETE-d8
Item number: Cay334720-25
15(S)-HETE-d8 is intended for use as an internal standard for the quantification of 15(S)-HETE (Cay-34720) by GC- or LC-MS. (±)15-HETE and 15(S)-HETE are formed via non-enzymatic and 15-lipoxygenase-mediated oxidation of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607), respectively. 15(R)-HETE is formed by...
| Keywords: | 15(S)-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid |
| Application: | Standard |
| CAS | 84807-87-4 |
| MW: | 328.5 D |
From 243.00€
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25-hydroxy Cholesterol
Item number: Cay11097-5
25-hydroxy Cholesterol is an oxysterol. It is formed from cholesterol by cholesterol-25-hydroxylase, and its production can be induced by inflammation or infection. 25-hydroxy Cholesterol suppresses endogenous cholesterol synthesis by binding to insulin-induced gene (INSIG) proteins and preventing sterol regulatory...
| Keywords: | 25-OH Cholesterol, cholest-5-ene-3beta,25-diol |
| Application: | Metabolic studies |
| CAS | 2140-46-7 |
| MW: | 402.7 D |
From 35.00€
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16,16-dimethyl Prostaglandin E2
Item number: Cay14750-1
16,16-dimethyl PGE2 is a competitive inhibitor of 15-hydroxy PGDH, but it is not a substrate for the enzyme. Because of its resistance to metabolism by 15-hydroxy PGDH, it has a prolonged half-life in vivo. 16,16-dimethyl PGE2 acts as an agonist on most EP receptor subtypes, and has been used experimentally to...
| Keywords: | 16,16-dimethyl PGE2, 9-oxo-11alpha,15R-dihydroxy-16,16-dimethyl-prosta-5Z,13E-dien-1-oic acid |
| Application: | PGDH inhibitor |
| CAS | 39746-25-3 |
| MW: | 380.5 D |
From 117.00€
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12-oxo Phytodienoic Acid
Item number: Cay88520-1
12-oxo Phytodienoic acid (OPDA) is a biologically active, immediate precursor of 7-epi jasmonic acid. In addition to its link with jasmonic acid activity, OPDA appears to play an independent role in mediating resistance to pathogens and pests. As an endogenous signal transducer, OPDA has been shown to increase...
| Keywords: | 12-oxo PDA, OPDA, 4-oxo-5alpha-2Z-pentenyl)-2-cyclopentene-1alpha-octanoic acid |
| Application: | Bioactive lipid assays |
| CAS | 85551-10-6 |
| MW: | 292.4 D |
From 95.00€
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PAF C-16
Item number: Cay60900-5
PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the "remodeling" and 'de novo' pathways. It is a potent mediator of neutrophil migration, and the production of reactive oxygen species, and IL-6 in human macrophages. It is a more potent mediator of...
| Keywords: | Platelet-activating Factor C-16, 1-O-hexadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine |
| Application: | Bioactive lipid assays |
| CAS | 74389-68-7 |
| MW: | 523.7 D |
From 49.00€
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Ciclesonide
Item number: LKT-C324091.100
Ciclesonide is an anti-inflammatory corticosteroid. Its active metabolite and several ciclesonide-acetal derivatives have been found to block RNA replication of the SARS-Cov-2 virus. Ciclesonide also inhibits lung cancer stem cells through Hedgehog signaling-mediated SOX2 regulation. Solubility: Insoluble in water....
| Keywords: | Alvesco, Omnaris, Zetonna, RPR251526, (R)-11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal... |
| Application: | Corticosteroid |
| CAS | 126544-47-6 |
| MW: | 540.7 D |
From 138.00€
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(±)13-HODE
Item number: Cay38600-100
(±)13-HODE is one of the two racemic monohydroxy fatty acids resulting from the non-enzymatic oxidation of linoleic acid. It is the principle hydroxylated fatty acid in human psoriatic skin scales, with a mean concentration of 17 ng/mg.Formal Name: (±)-13-hydroxy-9Z,11E-octadecadienoic acid. CAS Number: 18104-45-5....
| Keywords: | (±)-13-hydroxy-9Z,11E-octadecadienoic acid |
| Application: | Bioactive lipid studies |
| CAS | 18104-45-5 |
| MW: | 296.4 D |
From 197.00€
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