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Leukotriene D4
Item number: Cay20310-25
Leukotriene D4 (LTD4) is an active metabolite of LTC4 (Cay-20210) and a constituent of slow-reacting substance of anaphylaxis (SRS-A). It is formed via metabolism of LTC4 by gamma-glutamyl transpeptidase. Like LTC4, LTD4 (0.01-0.1 pM) induces contractions in isolated guinea pig parenchymal strips and tracheal...
| Keywords: | LTD4, 5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 73836-78-9 |
| MW: | 496.7 D |
From 197.00€
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13-Docosenamide
Item number: Cay90377-1
13-Docosenamide is the amide of docosenoic acid. It was first identified in the cerebrospinal fluid of sleep-deprived cats. It has also been detected in the cerebrospinal fluid of rats and humans. 13-Docosenamide causes reduced mobility and slightly lessened awareness in rats, whereas 9-octadecenamide induces...
| Keywords: | cis-13-Docosenamide, Armoslip E, Erucamide, 13Z-docosenamide |
| Application: | Cerebrospinal fluid constituent |
| CAS | 112-84-5 |
| MW: | 337.6 D |
From 35.00€
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Leukotriene C4
Item number: Cay20210-25
Leukotriene C4 (LTC4) is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. LTC4 is produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A)...
| Keywords: | LTC4, 5S-hydroxy-6R-(S-glutathionyl)-7E,9E,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 72025-60-6 |
| MW: | 625.8 D |
From 197.00€
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6-keto Prostaglandin F1alpha
Item number: Cay15210-1
6-keto Prostaglandin F1alpha (6-keto PGF1alpha) is the inactive, non-enzymatic hydrolysis product of PGI2. 6-keto PGF1alpha serves as a useful marker of PGI2 biosynthesis in vivo. When [3H]-PGI2 is injected into healthy human males, 6.6% of the radioactivity is recovered from urine as [3H]-6-keto PGF1alpha.Formal...
| Keywords: | 6-keto PGF1alpha, 6-oxo-9alpha,11alpha,15S-trihydroxy-prost-13E-en-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 58962-34-8 |
| MW: | 370.5 D |
From 133.00€
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Linoleic Acid
Item number: Cay90150-50
Linoleic acid is an essential omega-6 polyunsaturated fatty acid (PUFA). It is the most abundant PUFA in a variety of foods, and dietary sources of linoleic acid include vegetable oils, meats, nuts, seeds, and eggs. Linoleic acid (30 µM) increases migration of IEC-6 rat intestinal epithelial cells in a wound healing...
| Keywords: | 9,12-Octadecadienoic Acid, C18:2 n-6, C18:2(9Z,12Z), Telfairic Acid, 9Z,12Z-octadecadienoic acid |
| Application: | Bioactive lipid assays |
| CAS | 60-33-3 |
| MW: | 280.5 D |
From 29.00€
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5(S)-HETE-d8
Item number: Cay334230-25
5(S)-HETE-d8 is intended for use as an internal standard for the quantification of 5-HETE by GC- or LC-MS. (±)5-HETE is formed via non-enzymatic oxidation of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). 5(S)- and 5(R)-HETE are formed by lipoxygenase-mediated oxidation of arachidonic acid.Formal Name:...
| Keywords: | 5S-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid |
| Application: | Standard |
| CAS | 330796-62-8 |
| MW: | 328.5 D |
From 243.00€
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13,14-dihydro-15-keto Prostaglandin D2
Item number: Cay12610-1
13,14-dihydro-15-keto Prostaglandin D2 (13,14-dihydro-15-keto PGD2) is a metabolite of PGD2 (Cay-12010) which is formed through the 15-hydroxy PGDH pathway. 13,14-dihydro-15-keto PGD2 was recently identified as a selective agonist for the CRTH2/DP2 receptor. It also inhibits ion flux in a canine colonic mucosa...
| Keywords: | 13,14-dihydro-15-keto PGD2, 9alpha-hydroxy-11,15-dioxo-prost-5Z-en-1-oic acid |
| Application: | CRTH2 receptor agonist, DP2 receptor agonist |
| CAS | 59894-07-4 |
| MW: | 352.5 D |
From 178.00€
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Thromboxane B2-d4
Item number: Cay319030-25
Thromboxane B2-d4 (TXB2-d4) is intended for use as an internal standard for the quantification of TXB2 (Cay-19030) by GC- or LC-MS. TXB2 is a non-enzymatically derived, stable, inactive metabolite of TXA2, which is highly unstable. Serum levels of TXB2 positively correlate with platelet COX-1 activation. Urinary...
| Keywords: | TXB2-d4, 9alpha,11,15S-trihydroxy-thromba-5Z,13E-dien-1-oic-3,3,4,4-d4 acid |
| Application: | Standard |
| CAS | 1346112-79-5 |
| MW: | 374.5 D |
From 246.00€
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Licofelone
Item number: Cay10007692-10
Cross-talk between lipoxygenase (LO) and cyclooxygenase (COX) pathways has been observed in human osteoarthritic synovial explants which creates an arachidonic acid shunting phenomenon, stimulating interleukin-1beta (IL-1beta) synthesis. Licofelone is a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LO)...
| Keywords: | ML 3000, 6-(4-chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizine-5-acetic acid |
| Application: | COX-1/COX-2/5-LO dual inhibitor |
| CAS | 156897-06-2 |
| MW: | 379.9 D |
From 69.00€
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Tafluprost
Item number: Cay10005440-25
Tafluprost is a prodrug form of the FP receptor agonist tafluprost (free acid) (Cay-10005439) and a derivative of prostaglandin F2alpha (PGF2alpha, Cay-16010, Cay-16020). It decreases pupillary diameter in cats when applied topically at doses of 0.0001 or 0.001% v/v. Ocular administration of tafluprost (0.0005% v/v)...
| Keywords: | AFP-168, 15,15-difluoro-9alpha,11alpha-dihydroxy-16-phenoxy-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid, isopropyl... |
| Application: | FP receptor agonist |
| CAS | 209860-87-7 |
| MW: | 452.5 D |
From 153.00€
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1,2-Dipalmitoyl-sn-glycero-3-PC
Item number: Cay10009473-100
1,2-Dipalmitoyl-sn-glycero-3-PC (1,2-DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications. It has been used in the formation of proteoliposomes for implantation of gamma-glutamyl transpeptidase into human...
| Keywords: | 1,2-Dipalmitoyl-sn-glycero-3-Phosphatidylcholine, 16:0/16:0-PC, DPPC, L-Dipalmitoyl Lecithin, PC(16:0/16:0),... |
| Application: | Zwitterionic glycerophospholipid, lipid monolayer formation |
| CAS | 63-89-8 |
| MW: | 734.1 D |
135.00€
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Tauro-omega-muricholic Acid (sodium salt)
Item number: Cay28842-1
Tauro-omega-muricholic acid is a taurine-conjugated form of the secondary bile acid omega-muricholic acid (Cay-20292). Hepatic levels of tauro-omega-muricholic acid are decreased in mice following a diet supplemented with cholic, deoxycholic, chenodeoxycholic, or ursodeoxycholic acid and in a high-fat diet-induced...
| Keywords: | TOMCA, T-omega-MCA,... |
| Application: | Taurine-conjugated, secondary bile acid |
| CAS | 2456348-84-6 |
| MW: | 537.7 D |
From 263.00€
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