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Desacetylcinobufagin
Item number: Cay39822-1
Desacetylcinobufagin is an active metabolite of the cardiotonic steroid cinobufagin (Cay-19844). It is cytotoxic to HepG2, K562, and HL-60 cells (IC50s = 51.2, 50.1, and 7.5 µM, respectively).Formal Name: (5beta)-14,15beta-epoxy-3beta,16beta-dihydroxy-bufa-20,22-dienolide. CAS Number: 4026-95-3. Synonyms:...
| Keywords: | Deacetylcinobufagin, NSC 234203, (5beta)-14,15beta-epoxy-3beta,16beta-dihydroxy-bufa-20,22-dienolide |
| Application: | Cardiotonic steroid cinobufagin active metabolite |
| CAS | 4026-95-3 |
| MW: | 400.5 D |
From 48.00€
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15-deoxy-Delta12,14-Prostaglandin J2 serinol amide
Item number: Cay39917-1
15-deoxy-Delta12,14-Prostaglandin J2 serinol amide (15-deoxy-Delta12,14-PGJ2-SA) is a stable derivative of 15-deoxy-Delta12,14-PGJ2-2-glyceryl ester (Cay-10010132), which is a metabolite of PGD2 2-glyceryl ester.Formal Name:...
| Keywords: | 15-deoxy-Delta12,14-PGJ2-SA,... |
| Application: | Stable 15-deoxy-Delta12,14-PGJ2-2-glyceryl ester derivative |
| MW: | 389.5 D |
From 67.00€
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6beta-hydroxy Triamcinolone acetonide
Item number: Cay40122-1
6beta-hydroxy Triamcinolone acetonide is a metabolite of the synthetic corticosteroid triamcinolone acetonide (Cay-18026). It is formed from triamcinolone acetonide by the cytochrome P450 (CYP) isoforms CYP3A4, CYP3A5, and CYP3A7. 6beta-hydroxy Triamcinolone acetonide has been found in wastewater effluent.Formal...
| Keywords: | 6beta-hydroxy TrA, 9-fluoro-6beta,11beta,21-trihydroxy-16alpha,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione |
| Application: | Triamcinolone acetonide metabolite |
| CAS | 3869-32-7 |
| MW: | 450.5 D |
650.00€
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Norbixin (hydrate)
Item number: Cay40132-1
Norbixin is a carotenoid that has been found in B. orellana and has diverse biological activities. It binds to peroxisome proliferator-activated receptor gamma (PPARgamma) in a cell-free assay (Ki = 1.15 µM). Norbixin (47.7 mg/kg) attenuates hyperglycemia, hyperinsulinemia, and insulin resistance, as well as...
| Keywords: | 4,8,13,17-tetramethyl-2E,4E,6E,8E,10E,12E,14E,16E,18E-eicosanonaenedioic acid, hydrate |
| Application: | Bioactive carotenoid |
| MW: | 380.5 D |
From 204.00€
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Biotin Sulfoxide
Item number: Cay40172-10
Biotin sulfoxide is a racemic mixture of the biotin (Cay-22582) metabolites biotin (R)-sulfoxide and biotin (S)-sulfoxide (Cay-34145).Formal Name: 5-((3aS,4S,6aR)-5-oxido-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid. CAS Number: 23015-53-4. Synonyms: (±)-Biotin Sulfoxide, D,L-Biotin Sulfoxide....
| Keywords: | (±)-Biotin Sulfoxide, D,L-Biotin Sulfoxide, 5-((3aS,4S,6aR)-5-oxido-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic... |
| Application: | Racemic mixture, biotin metabolites |
| CAS | 23015-53-4 |
| MW: | 260.3 D |
From 54.00€
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G0-C14 analog
Item number: Cay40194-1
G0-C14 analog is a derivative of the ionizable cationic lipid G0-C14.Formal Name: 3,3',3'',3'''-(ethane-1,2-diylbis(azanetriyl))tetrakis(N-(2-(bis(2-hydroxytetradecyl)amino)ethyl)propanamide). CAS Number: 2935435-86-0. Molecular Formula: C134H272N10O12. Formula Weight: 2215.7. Purity: >95% (mixture of isomers)....
| Keywords: | 3,3',3'',3'''-(ethane-1,2-diylbis(azanetriyl))tetrakis(N-(2-(bis(2-hydroxytetradecyl)amino)ethyl)propanamide) |
| Application: | Ionizable cationic lipid G0-C14 derivative |
| CAS | 2935435-86-0 |
| MW: | 2215.7 D |
From 204.00€
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9322-O16B
Item number: Cay40208-10
9322-O16B is an ionizable cationic lipid. It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro. LNPs containing 9322-O16B and encapsulating mRNA encoding chimeric antigen receptors (CARs) have been used in the generation of anti-CD19 CAR macrophages with anticancer...
| Keywords: | bis(2-(dodecyldisulfaneyl)ethyl) 3,3'-((3-(2-methyl-1H-imidazol-1-yl)propyl)azanediyl)dipropionate |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 2909427-23-0 |
| MW: | 804.3 D |
From 158.00€
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IMCTA-C14 (trifluoroacetate salt)
Item number: Cay40230-5
IMCTA-C14 is a detergent and derivative of the microbial metabolite 4-trehalosamine (Cay-40229). It has a critical micelle concentration (CMC) of 0.11 mM and a hydrophilic-lipophilic balance (HLB) value of 9.72. IMCTA-C14 (0.05 and 0.5%) extracts proteins, including membrane proteins, from OVK18 ovarian cancer...
| Keywords: | (2R,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6S)-3,4-dihydroxy-6-(hydroxymethyl)-5-(tetradecylamino)tetrahydro-2H-pyran-2-yl)oxy)-6-(... |
| Application: | 4-trehalosamine derivative, detergent |
| MW: | 651.7 D |
582.00€
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Ouabain (hydrate)
Item number: Cay14319-1
Ouabain is a cardiac glycoside that has been found in S. gratus and has diverse biological activities. It inhibits the Na+/K+-ATPase isoforms alpha1beta1 and alpha2beta1 and human-ether-a-go-go (hERG), also known as Kv11.1 (IC50s = 97, 90, and 15.2 nM, respectively). Ouabain reduces the proliferation of PC3 prostate...
| Keywords: | g-Strophanthin, 3beta-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-1beta,5beta,11alpha,14,19-pentahydroxy-card-20(22)-enolide,... |
| Application: | Bioactive cardiac glycoside |
| CAS | 340169-01-9 |
| MW: | 584.7 D |
From 54.00€
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1-O-Dodecyl-rac-glycerol
Item number: Cay17441-1
1-O-Dodecyl-rac-glycerol is an alkyl glyceryl ether. It is also a nonionic surfactant. 1-O-Dodecyl-rac-glycerol increases autolysin activity in S. faecium and inhibits peptidoglycan synthesis in S. mutans. It induces mouse peritoneal macrophage activation ex vivo when administered at a dose of 100 ng/animal....
| Keywords: | 1-O-Lauryl-rac-glycerol, 2,3-Dihydroxypropyl dodecyl ether, DDG, Lauryl glyceryl ether, MG(O-12:0/0:0/0:0), NSC 38645,... |
| Application: | Alkyl glyceryl ether, nonionic surfactant |
| CAS | 1561-07-5 |
| MW: | 260.4 D |
From 136.00€
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12-keto Chenodeoxycholic Acid
Item number: Cay30838-1
12-keto Chenodeoxycholic acid (12-keto CDCA) is an intermediate in the semisynthetic synthesis of ursodeoxycholic acid (Cay-31016, Cay-15121) and chenodeoxycholic acid (Cay-10011286, Cay-35346) from the primary bile acid cholic acid (Cay-20250). 12-keto CDCA has been found in the gastric tissues of C57BL/6J mice, KM...
| Keywords: | 12-keto CDCA, 12-oxo CDCA, 12-oxo Chenodeoxycholic Acid, 3alpha,7alpha-Dihydroxy-12-keto-5beta-cholanic acid,... |
| Application: | Ursodeoxycholic acid / chenodeoxycholic acid synthesis intermediate |
| CAS | 2458-08-4 |
| MW: | 406.6 D |
From 40.00€
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Acetyl-DL-carnitine (chloride)
Item number: Cay31015-100
Acetyl-DL-carnitine is a racemic mixture of the short-chain acylcarnitine acetyl-D-carnitine and the mitochondrial metabolite acetyl-L-carnitine (Cay-16948). It increases the oxidation rate of the branched-chain 2-oxo acid 3-methyl-2-butanoate in isolated rat muscle mitochondria in the absence of carnitine when used...
| Keywords: | (±)-Acetylcarnitine, C2:0 Carnitine, CAR 2:0, DL-Acetylcarnitine, DL-Carnitine acetyl ester,... |
| Application: | Acetyl-D-carnitine / acetyl-L-carnitine racemic mixture |
| CAS | 2504-11-2 |
| MW: | 239.7 D |
From 62.00€
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