Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

Lipids are small,  organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids.... read more »
Close window
Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

314 from 320 pages
No results were found for the filter!
A1-28
A1-28

Item number: Cay39590-10

A1-28 is a disulfide bond-containing ionizable cationic lipid. It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of CRISPR complementary single-guide RNA (sgRNA) and Cas9 mRNA for genome editing in vitro.Formal Name: bis(2-(dodecyldisulfaneyl)ethyl)...
Keywords: AMAP-O16B, bis(2-(dodecyldisulfaneyl)ethyl)...
Application: Ionizable cationic lipid, LNP formation
MW: 1142.9 D
From 219.00€ *
Review
DU-14
DU-14

Item number: Cay39665-1

DU-14 is a steroid sulfatase inhibitor (IC50 = 55.8 nM). It inhibits the proliferation of MCF-7 breast cancer cells (IC50 = 38.7 nM). In vivo, DU-14 (30 mg/kg), in combination with the steroid precursor dehydroepiandrosterone sulfate (DHEAS, Cay-15873), potentiates DHEAS reversal of scopolamine-induced amnesia in...
Keywords: (p-O-Sulfamoyl)-N-Tetradecanoyltyramine, N-[2-[4-[(aminosulfonyl)oxy]phenyl]ethyl]-tetradecanamide
Application: Steroid sulfatase inhibitor
CAS 186303-55-9
MW: 426.6 D
From 35.00€ *
Review
BODIPY 480/508-Cholesteryl Linoleate
BODIPY 480/508-Cholesteryl Linoleate

Item number: Cay39684-1

BODIPY 480/508-cholesteryl linoleate is a cell-permeable and fluorescently tagged derivative of cholesteryl linoleate (Cay-22597). BODIPY 480/508-cholesteryl linoleate displays excitation/emission maxima of 480/508 nm, respectively, and has been used to monitor cholesterol trafficking in isolated human...
Keywords: BODIPY 480/508-Cholesterol Linoleate,...
Application: Fluorescently tagged cholesterol ester, cholesterol trafficking monitoring
CAS 2260795-60-4
MW: 839 D
From 272.00€ *
Review
BODIPY 480/508-Cholesteryl Oleate
BODIPY 480/508-Cholesteryl Oleate

Item number: Cay39685-1

BODIPY 480/508-cholesteryl oleate is a cell-permeable and fluorescently tagged derivative of cholesteryl oleate (Cay-26472). BODIPY 480/508-cholesteryl oleate displays excitation/emission maxima of 480/508 nm, respectively, and has been used to monitor cholesterol trafficking in HeLa cells.Formal Name:...
Keywords: BODIPY 480/508-Cholesterol Oleate,...
Application: Fluorescently tagged cholesterol ester, cholesterol trafficking monitoring
MW: 841.1 D
From 136.00€ *
Review
IAJD93
IAJD93

Item number: Cay39688-10

IAJD93 is an ionizable amphiphilic Janus dendrimer (IAJD) delivery system for mRNA (pKa = 6.25). It co-assembles with mRNA to form dendrimersome nanoparticles (DNPs) in acetate buffer. IAJD93 co-assembled with luciferase mRNA delivers the mRNA to the spleen, liver, lungs, and lymph nodes in mice.Formal Name:...
Keywords: Ionizable Amphiphilic Janus Dendrimer 93, 3-((2-ethylhexyl)oxy)-2,2-bis(((2-ethylhexyl)oxy)methyl)propyl...
Application: Ionizable amphiphilic Janus dendrimer mRNA delivery system, dendrimersome nanoparticle formation
MW: 671 D
From 136.00€ *
Review
IAJD249
IAJD249

Item number: Cay39689-10

IAJD249 is an ionizable amphiphilic Janus dendrimer (IAJD) delivery system for mRNA (pKa = 6.35). It co-assembles with mRNA to form dendrimersome nanoparticles (DNPs) in acetate buffer. IAJD249 co-assembled with luciferase mRNA delivers the mRNA to the spleen, liver, lungs, and lymph nodes in mice.Formal Name:...
Keywords: Ionizable Amphiphilic Janus Dendrimer 249, 3-(octyloxy)-2,2-bis((octyloxy)methyl)propyl...
Application: Ionizable amphiphilic Janus dendrimer mRNA delivery system, dendrimersome nanoparticle formation
MW: 671 D
From 171.00€ *
Review
Tirzepatide (sodium salt)
Tirzepatide (sodium salt)

Item number: Cay39748-1

Tirzepatide is an agonist of glucagon-like peptide 1 receptor (GLP-1R) and gastric inhibitory polypeptide (GIP) receptor. It induces cAMP production in HEK293 cells expressing human GLP-1R or human GIP receptor (EC50s = 6.54 and 1.01 nM, respectively). Tirzepatide (100 nM) induces receptor internalization in HEK293...
Keywords: LY3298176,...
Application: Dual GLP-1R / GIPR agonist
MW: 4813.5 D
From 39.00€ *
Review
Lipid 331
Lipid 331

Item number: Cay39771-1

Lipid 331 is a biodegradable cyclic ionizable cationic lipid (pKa = 7.53) that has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. LNPs containing lipid 331 and encapsulating 5-methoxyuridine-modified mRNA encoding ovalbumin induce IFN regulatory factor (IRF)...
Keywords: di((9Z,12Z)-octadeca-9,12-dien-1-yl)...
Application: Ionizable cationic lipid, LNP formation
MW: 978.5 D
From 149.00€ *
Review
Ganoderenic Acid D
Ganoderenic Acid D

Item number: Cay39774-1

Ganoderenic acid D is a triterpenoid originally isolated from G. lucidum and has diverse biological activities. It inhibits angiotensin-converting enzyme (ACE, IC50 = 734 µM). Ganoderenic acid D is cytotoxic to HepG2 liver, HeLa cervical, and Caco-2 colon cancer cells (IC50s = 0.14, 0.18, and 0.26 mg/ml,...
Keywords: (7beta,20E)-7-hydroxy-3,11,15,23-tetraoxo-lanosta-8,20(22)-dien-26-oic acid
Application: Bioactive triterpenoid
CAS 100665-43-8
MW: 512.6 D
From 95.00€ *
Review
Ganodermanondiol
Ganodermanondiol

Item number: Cay39776-1

Ganodermanondiol is a triterpenoid that has been found in G. lucidum and has diverse biological activities. It inhibits the proliferation of Meth A sarcoma and LLC1 lung carcinoma cells (IC50s = 3.4 and 12.5 µg/ml, respectively). Ganodermanondiol (20 µM) reduces the viability of RAW 264.7 macrophages. It inhibits...
Keywords: 24S,25-dihydroxy-lanosta-7,9(11)-dien-3-one
Application: Bioactive triterpenoid
CAS 107900-76-5
MW: 456.7 D
From 75.00€ *
Review
Benzydamine (hydrochloride)
Benzydamine (hydrochloride)

Item number: Cay39808-10

Benzydamine is a non-steroidal anti-inflammatory drug (NSAID). It decreases the viability of THP-1 monocytes, Saos-2 osteosarcoma, and HGF-1 gingival cancer cells (IC50s = 59.08, 30.79, and 52.06 µg/ml, respectively). Benzydamine (10 µg/ml) reduces LPS-induced increases in the levels of IL-6 and TNF-alpha secreted...
Keywords: N,N-dimethyl-3-[[1-(phenylmethyl)-1H-indazol-3-yl]oxy]-1-propanamine, monohydrochloride
Application: NSAID, COX inhibitor
CAS 132-69-4
MW: 345.9 D
From 40.00€ *
Review
5,7,3',4',5'-Pentamethoxyflavone
5,7,3',4',5'-Pentamethoxyflavone

Item number: Cay39820-10

5,7,3',4',5'-Pentamethoxyflavone is a flavonoid that has been found in M. paniculata and has diverse biological activities. It inhibits pancreatic lipase in a cell-free assay and reduces lipid accumulation in 3T3-L1 adipocytes in a concentration-dependent manner. 5,7,3',4',5'-Pentamethoxyflavone inhibits...
Keywords: 3',4',5',5,7-Pentamethoxyflavone, 5,7,3',4',5'-PMF, 5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one
Application: Bioactive flavonoid
CAS 53350-26-8
MW: 372.4 D
From 62.00€ *
Review
314 from 320 pages