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1-Palmitoyl-2-Oleoyl-sn-glycero-3-PS (sodium salt)
Item number: Cay20068-1
1-Palmitoyl-2-oleoyl-sn-glycero-3-PS (1,2-POPS) is an anionic phospholipid that contains palmitic acid (Cay-10006627) and oleic acid (Cay-90260, Cay-24659) at the sn-1 and sn-2 positions, respectively. It has been used in the synthesis of lipid membranes and synthetic high-density lipoproteins.Formal Name:...
| Keywords: | 1,2-POPS, 16:0/18:1-PS, 1-Hexadecanoyl-2-Octadecenoyl-sn-glycero-3-Phosphatidylserine,... |
| Application: | Phospholipid |
| CAS | 321863-21-2 |
| MW: | 784 D |
From 35.00€
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7alpha-Hydroxy-3-oxocholest-4-enoic Acid-d3
Item number: Cay29537-1
7alpha-Hydroxy-3-oxocholest-4-enoic acid-d3 is intended for use as an internal standard for the quantification of 7alpha-hydroxy-3-oxocholest-4-enoic acid by GC- or LC-MS. 7alpha-Hydroxy-3-oxocholest-4-enoic acid is a metabolite of the endogenous liver X receptor (LXR) agonist 25(R)-27-hydroxy cholesterol...
| Keywords: | 7alpha-hydroxy-3-oxo-cholest-4-en-26-oic-27,27,27-d3 acid |
| Application: | GC-MS, LC-MS internal standard, quantification, metabolite |
| CAS | 2342573-89-9 |
| MW: | 433.6 D |
890.00€
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HWL-088
Item number: Cay30227-1
HWL-088 is an agonist of free fatty acid receptor 1 (FFAR1/GPR40) and peroxisome proliferator-activated receptor delta (PPARdelta). It induces calcium mobilization in CHO cells expressing human FFAR1/GPR40 (EC50 = 18.9 nM) and transactivation of PPARdelta in a reporter assay using HEK293 cells (EC50 = 570.9 nM)....
| Keywords: | 2-[2-fluoro-4-[(2'-methyl[1,1'-biphenyl]-3-yl)methoxy]phenoxy]-acetic acid |
| Application: | FFAR1(GPR40)/PPARdelta agonist |
| CAS | 2378617-96-8 |
| MW: | 366.4 D |
From 103.00€
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Tigloyl-L-carnitine (chloride)
Item number: Cay30994-1
Tigloyl-L-carnitine is a short-chain acylcarnitine composed of tiglic acid and L-carnitine (Cay-21489). Plasma levels of tigloyl-L-carnitine are increased in several melanoma mouse xenograft models compared with non-tumor bearing mice. Tigloyl-L-carnitine levels are increased in dried blood spots from neonates with...
| Keywords: | C5:1 Carnitine, CAR 5:1, L-Carnitine tigloyl ester, L-Carnitine tiglyl ester, L-Tigloylcarnitine, L-Tiglylcarnitine,... |
| Application: | Short-chain acylcarnitine |
| MW: | 279.8 D |
From 35.00€
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Marein
Item number: Cay33213-1
Marein is a glucoside chalcone that has been found in C. tinctoria and has diverse biological activities, including antioxidant, enzyme inhibitory, antidiabetic, and anti-inflammatory properties. It scavenges DPPH (Cay-14805) radicals (IC50 = 48.35 µM) in a cell-free assay and is an inhibitor of EGFR (IC50 = 19.94...
| Keywords: | (2E)-3-(3,4-dihydroxyphenyl)-1-[4-(beta-D-glucopyranosyloxy)-2,3-dihydroxyphenyl]-2-propen-1-one |
| Application: | Bioactive glucoside chalcone |
| CAS | 535-96-6 |
| MW: | 450.4 D |
From 66.00€
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Aloenin
Item number: Cay35859-1
Aloenin is a polyketide synthase-derived glucoside that has been found in Aloe and has diverse biological activities. It is an inhibitor of pancreatic lipase (IC50 = 14.95 µg/ml) and beta-secretase (BACE). Aloenin is also an inhibitor of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH, IC50s = 33.1 and...
| Keywords: | Aloearbonaside, Aloenin A, 6-[2-(beta-D-glucopyranosyloxy)-4-hydroxy-6-methylphenyl]-4-methoxy-2H-pyran-2-one |
| Application: | Bioactive polyketide glucoside |
| CAS | 38412-46-3 |
| MW: | 410.4 D |
From 35.00€
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Antrodin A
Item number: Cay36094-1
Antrodin A is a microbial metabolite originally found in A. camphorata that has antiviral and hepatoprotective activities. It is an inhibitor of hepatitis C virus (HCV) protease (IC50 = 0.9 µg/ml). Antrodin A reduces cytotoxicity in Vero cells infected with herpes simplex virus 1 (HSV-1) or HSV-2 (IC50s = 5.8 and...
| Keywords: | Camphorataanhydride A, 3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-4-(2-methylpropyl)-2,5-furandione |
| Application: | Microbial metabolite, antiviral / hepatoprotective agent |
| CAS | 656830-24-9 |
| MW: | 314.4 D |
From 67.00€
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4-Biphenylacetic Acid
Item number: Cay38116-100
4-Biphenylacetic acid is a non-steroidal anti-inflammatory drug (NSAID) and an active metabolite of the prodrug fenbufen (Cay-28851). It inhibits prostaglandin E2 (PGE2, Cay-14010) synthesis in a cell-free assay (IC50 = 3.2 µM). In vivo, 4-biphenylacetic acid (2 mg/kg) suppresses UV-induced erythema in guinea pigs....
| Keywords: | p-Biphenylacetic Acid, Cl-83544, Felbinac, LY601017, NSC 16284, [1,1'-biphenyl]-4-acetic acid |
| Application: | NSAID, active fenbufen metabolite |
| CAS | 5728-52-9 |
| MW: | 212.2 D |
From 48.00€
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IMM-H007
Item number: Cay38774-1
IMM-H007 is an activator of AMP-activated protein kinase (AMPK) and an antagonist of TGF-beta1. It increases AMPK activity in HepG2 cell lysates when used at concentrations ranging from 1 to 100 µM. IMM-H007 binds to TGF-beta1 (Kd = 0.2098 µM) and inhibits the binding of TGF-beta1 to TGF-beta receptor type 2...
| Keywords: | N-(3-hydroxyphenyl)-adenosine 2',3',5'-triacetate |
| Application: | AMPK activator, TGF-beta1 antagonist |
| CAS | 1221412-23-2 |
| MW: | 485.5 D |
From 70.00€
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5-(4'-(Azidomethyl)(1,1'-biphenyl)-2-yl)-2H-tetrazole
Item number: Cay38780-1
5-(4'-(Azidomethyl)(1,1'-biphenyl)-2-yl)-2H-tetrazole (AZTT) is a potential impurity found in commercial preparations of tetrazole-containing sartans, including losartan, irbesartan, and valsartan.CAS Number: 152708-24-2. Synonyms: AZTT. Molecular Formula: C14H11N7. Formula Weight: 277.3. Purity: >95%. Formulation:...
| Keywords: | AZTT |
| Application: | Potential impurity in commercial tetrazole-containing sartan preparations |
| CAS | 152708-24-2 |
| MW: | 277.3 D |
From 48.00€
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Phellopterin
Item number: Cay38965-1
Phellopterin is a furanocoumarin that has been found in A. dahurica and has diverse biological activities. It is an antagonist of GABAA receptors (IC50 = 360 nM for the rat receptor). Phellopterin (20 µM) decreases LPS-induced secretion of prostaglandin E2 (PGE2, Cay-14010) from primary rat peritoneal macrophages....
| Keywords: | NSC 152469, 7-butyl-5-hydroxy-2-methyl-2-(4-methyl-3-penten-1-yl)-2H-1-benzopyran-6-carboxylic acid |
| Application: | Bioactive furanocoumarin |
| CAS | 2543-94-4 |
| MW: | 300.3 D |
From 121.00€
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PAMAM Dendrimer G0.0 Amine (water solution)
Item number: Cay39053-1
PAMAM dendrimer G0.0 amine (PAMAM G0.0) is the polyamidoamine (PAMAM) core with amine termini on which other PAMAM dendrimers are synthesized. It is approximately 15 Å in diameter and has 4 surface groups. PAMAM G0.0 is an antagonist for the pore-forming channels anthrax toxin protective antigen 63 (PA63, IC50 = 231...
| Keywords: | PAMAM G0.0, Polyamidoamine Dendrimer G0.0, 3,3',3'',3'''-(1,2-ethanediyldinitrilo)tetrakis[N-(2-aminoethyl)-propanamide |
| Application: | Amine-terminated PAMAM dendrimer |
| CAS | 155773-72-1 |
| MW: | 516.7 D |
From 35.00€
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