Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

Lipids are small,  organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids.... read more »
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Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

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Chonglou Saponin VII
Chonglou Saponin VII

Item number: Cay39251-1

Chonglou saponin VII is a steroid saponin that has been found in P. polyphylla and has anticancer activities. It inhibits the proliferation of HepG2 cells and HepG2 cells resistant to doxorubicin (HepG2/ADR cells) when used at concentrations of 1.98 and 2.97 µM. Chonglou saponin VII (1.98 µM) reduces ADR resistance...
Keywords: Paris Saponin VII, PS VII, (3beta,25R)-17-hydroxyspirost-5-en-3-yl...
Application: Steroid saponin, anticancer agent
CAS 68124-04-9
MW: 1031.2 D
From 133.00€ *
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Cardiolipin (14:1/14:1/14:1/14:1) (sodium salt)
Cardiolipin (14:1/14:1/14:1/14:1) (sodium salt)

Item number: Cay39280-1

Cardiolipin (14:1/14:1/14:1/14:1) is an anionic phospholipid containing the monounsaturated fatty acid myristoleic acid (Cay-9002461).Formal Name: (9Z,9'Z,9''Z,9'''Z)-9-Tetradecenoic acid, 1,1',1'',1'''-[(2R,14R)-5,8,11-trihydroxy-5,11-dioxido-4,6,10,12-tetraoxa-5,11-diophosphapentadecane-1,2,14,15-tetrayl] ester,...
Keywords: 14:1 Cardiolipin, Tetramyristoleoyl Cardiolipin, (9Z,9'Z,9''Z,9'''Z)-9-Tetradecenoic acid,...
Application: Phospholipid
CAS 2260669-33-6
MW: 1277.6 D
45.00€ *
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244cis
244cis

Item number: Cay39284-10

244cis is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs). LNPs containing 244cis and encapsulating an mRNA reporter specifically accumulate in the lungs and induce lower serum chemokine (C-C motif) ligand 2 (CCL2) levels than LNPs containing SM-102 (Cay-33474) in mice....
Keywords: di((Z)-non-2-en-1-yl) 9,9'-((2-(4-(9-(((Z)-non-2-en-1-yl)oxy)-9-oxononyl)piperazin-1-yl)ethyl)azanediyl)dinonanoate
Application: Ionizable cationic lipid, LNP formation
MW: 970.6 D
From 125.00€ *
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Cholesterol (plant)
Cholesterol (plant)

Item number: Cay39448-1

Cholesterol is a minor sterol produced in plant cells and a component of plant surface lipids. Cholesterol content in plants is generally several hundreds- to thousands-fold less than that of mammalian cells. It is a precursor in the synthesis of various bioactive plant metabolites, including steroidal...
Keywords: NSC 8798, Provitamin D, (3beta)-cholest-5-en-3-ol
Application: Minor plant sterol
CAS 57-88-5
MW: 386.7 D
From 100.00€ *
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SM-102 N-oxide
SM-102 N-oxide

Item number: Cay39636-1

SM-102 N-oxide is potential impurity in commercial preparations of SM-102.Formal Name: 8-(heptadecan-9-yloxy)-N-(2-hydroxyethyl)-8-oxo-N-(6-oxo-6-(undecyloxy)hexyl)octan-1-amine oxide. CAS Number: 2824195-50-6. Synonyms: CAY10779 N-oxide, Lipid H N-oxide, LNP-102 N-oxide. Molecular Formula: C44H87NO6. Formula...
Keywords: CAY10779 N-oxide, Lipid H N-oxide, LNP-102 N-oxide,...
Application: Commercial SM-102 preparation potential impurity
CAS 2824195-50-6
MW: 726.2 D
From 48.00€ *
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10-Chloroestra-1,4-diene-3,17-dione
10-Chloroestra-1,4-diene-3,17-dione

Item number: Cay39758-1

10-Chloroestra-1,4-diene-3,17-dione is a sterone agonist of estrogen receptor alpha (ERalpha). It increases reporter gene expression in S. cerevisiae (EC50 = 0.36 nM for the human receptor). It also is an aromatase inhibitor (IC50 = 2.4 µM).Formal Name: 10-chloro-estra-1,4-diene-3,17-dione. CAS Number: 91413-55-7....
Keywords: 10-chloro-1,4-Estradiene, 10-chloro-estra-1,4-diene-3,17-dione
Application: Sterone ERalpha agonist
CAS 91413-55-7
MW: 304.8 D
From 41.00€ *
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ALC-0315 N-oxide
ALC-0315 N-oxide

Item number: Cay39797-1

ALC-0315 N-oxide is a potential impurity in commercial preparations of the ionizable cationic amino lipid ALC-0315.Formal Name: 6-((2-hexyldecanoyl)oxy)-N-(6-((2-hexyldecanoyl)oxy)hexyl)-N-(4-hydroxybutyl)hexan-1-amine oxide. Molecular Formula: C48H95NO6. Formula Weight: 782.3. Purity: >98%. Formulation: (Request...
Keywords: 6-((2-hexyldecanoyl)oxy)-N-(6-((2-hexyldecanoyl)oxy)hexyl)-N-(4-hydroxybutyl)hexan-1-amine oxide
Application: Commercial ALC-0315 preparation potential impurity
MW: 782.3 D
From 49.00€ *
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S-Geranylgeranyl-L-glutathione
S-Geranylgeranyl-L-glutathione

Item number: Cay9004116-1

S-Geranylgeranyl-L-glutathione is a ligand of the orphan G protein-coupled receptor (GPCR) P2RY8. It selectively induces internalization of P2RY8 over sphingosine-1-phosphate receptor 2 (S1P2), GPR55, cysteinyl leukotriene receptor 1 (CysLT1 receptor), and CysLT2 receptor at 100 nM. S-Geranylgeranyl-L-glutathione...
Keywords: GGG,...
Application: P2RY8 ligand
CAS 2364639-42-7
MW: 579.8 D
From 35.00€ *
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DLin-MC4-DMA
DLin-MC4-DMA

Item number: Cay39732-10

DLin-MC4-DMA is an ionizable cationic lipid (pKa = 6.93). Lipid nanoparticles (LNPs) containing DLin-MC4-DMA and encapsulating siRNA for the gene encoding mouse coagulation factor VII (F7) reduce its gene expression levels in mice.Formal Name: 5-(dimethylamino)-pentanoic acid,...
Keywords: MC4, 5-(dimethylamino)-pentanoic acid, (10Z,13Z)-1-(9Z,12Z)-9,12-octadecadien-1-yl-10,13-nonadecadien-1-yl ester
Application: Ionizable cationic lipid
CAS 1226909-66-5
MW: 656.1 D
From 193.00€ *
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Colneleic Acid
Colneleic Acid

Item number: Cay10005076-100

Colneleic acid is a divinyl ether oxylipin and an active metabolite of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) that has been found in potatoes. It is formed from linoleic acid by 9-lipoxygenase (9-LO) via a (±)9-HpODE (Cay-10705) intermediate and divinyl ether synthase. Colneleic acid decreases P....
Keywords: FA 18:3,O, 9-[(1E,3Z)-1,3-nonadien-1-yloxy]-8E-nonenoic acid
Application: Oxylipin
CAS 52761-34-9
MW: 294.4 D
472.00€ *
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Pinolenic Acid ethyl ester
Pinolenic Acid ethyl ester

Item number: Cay10008658-1

Pinolenic acid is a polyunsaturated fatty acid found in Korean pine (Pinus orientalis) and maritime pine (Pinus pinaster) seed oils. Both oils have been found to have lipid-lowering properties. A diet containing maritime pine seed oil (MPSO) lowered high-density lipoprotein and ApoA1 levels in transgenic mice...
Keywords: 5Z,9Z,12Z-octadecatrienoic acid, ethyl ester
Application: Bioactive lipid assays
CAS 493015-74-0
MW: 306.5 D
From 28.00€ *
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TK05
TK05

Item number: Cay19793-1

TK05 is an inhibitor of leukotriene C4 (LTC4) synthase (IC50 = 95 nM). It is selective for LTC4 synthase over microsomal prostaglandin E synthase-1 (mPGES-1), microsomal glutathione S-transferase 2 (GST2), and 5-lipoxygenase (5-LO) at 10 µM. TK05 (1 µM) inhibits LTC4 synthase in Mono-Mac-6 leukemia cells and...
Keywords: 5-[[5-[(4-chlorophenyl)(cyclopropylmethyl)amino]-2-pyridinyl]carbonyl]-2-(4-methoxybenzoyl)-benzoic acid
Application: LTC4 synthase inhibitor
CAS 1245734-61-5
MW: 541 D
From 153.00€ *
Review
310 from 320 pages