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OC2-K3-E10
Item number: Cay38243-1
OC2-K3-E10 is an ionizable cationic lipid (pKa = 6.8). It has been used in the formation of lipid nanoparticles (LNPs) for the delivery of CRISPR complementary single-guide RNA (sgRNA) and Cas9 mRNA for genome editing in transgenic mice.Formal Name:...
| Keywords: | I-28, 3,3'-((2-hydroxyethyl)azanediyl)bis(N-(3-(bis(2-hydroxydecyl)amino)propyl)propanamide) |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 942.5 D |
From 103.00€
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Lipid CL1
Item number: Cay38320-10
Lipid CL1 is an ionizable cationic trialkyl lipid that has been used in the formation of lipid nanoparticles (LNPs). LNPs containing lipid CL1 and encapsulating mRNA encoding human erythropoietin (EPO) increase blood EPO protein levels in mice.Formal Name: 5-(dimethylamino)-pentanoic acid,...
| Keywords: | 5-(dimethylamino)-pentanoic acid, (6Z)-1,2-di-(4Z)-4-decen-1-yl-6-dodecen-1-yl ester |
| Application: | Ionizable cationic trialkyl lipid, LNP formation |
| CAS | 1450888-71-7 |
| MW: | 588 D |
From 239.00€
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C13-112-tri-tail
Item number: Cay38383-1
C13-112-tri-trail is an ionizable cationic lipid.Formal Name: 14-(2-hydroxytridecyl)-17,20-dioxa-14,23-diazahexatriacontane-12,25-diol. CAS Number: 1381861-96-6. Molecular Formula: C45H94N2O5. Formula Weight: 743.2. Purity: >90%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMSO:...
| Keywords: | 14-(2-hydroxytridecyl)-17,20-dioxa-14,23-diazahexatriacontane-12,25-diol |
| Application: | Ionizable cationic lipid |
| CAS | 1381861-96-6 |
| MW: | 743.2 D |
From 35.00€
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Lipid M
Item number: Cay38775-1
Lipid M is an ionizable cationic lipid (pKa = 6.75) that has been used in the generation of lipid nanoparticles (LNPs) for mRNA delivery in vivo. LNPs containing lipid M and encapsulating mRNA encoding influenza virus genes increase anti-influenza virus IgG titers in cynomolgus monkeys without inducing local edema,...
| Keywords: | 2-octyl-decanoic acid, 7-[(2-hydroxyethyl)[8-(nonyloxy)-8-oxooctyl]amino]heptyl ester |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 2089251-57-8 |
| MW: | 710.2 D |
From 126.00€
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1,2-Dihexanoyl-sn-glycero-3-PS (sodium salt)
Item number: Cay39190-1
1,2-Dihexanoyl-sn-glycero-3-PS is a phospholipid containing hexanoic acid at the sn-1 and sn-2 positions.Formal Name: (2S,8R)-2-amino-5-hydroxy-11-oxo-8-[(1-oxohexyl)oxy]-4,6,10-trioxa-5-phosphahexadecanoic acid, 5-oxide, monosodium salt. CAS Number: 321862-85-5. Synonyms:...
| Keywords: | 1,2-Dicaproyl-sn-glycero-3-phosphatidylserine, 1,2-Dicaproyl-sn-glycero-3-phosphoserine,... |
| Application: | Phospholipid |
| CAS | 321862-85-5 |
| MW: | 477.4 D |
From 40.00€
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DLin-MC2-DMA
Item number: Cay39731-1
DLin-MC2-DMA is an ionizable cationic lipid (pKa = 5.64) that has been used in the formation of lipid nanoparticles (LNPs). LNPs containing DLin-MC2-DMA and encapsulating siRNA targeting mRNA encoding mouse coagulation Factor VII (FVII) reduce hepatic levels of FVII in mice (ED50 = 0.6 mg/kg).Formal Name:...
| Keywords: | MC2, N,N-dimethyl-beta-alanine (10Z,13Z)-1-(9Z,12Z)-9,12-octadecadien-1-yl-10,13-nonadecadien-1-yl ester |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 1221271-55-1 |
| MW: | 628.1 D |
From 35.00€
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Lipid C2
Item number: Cay39783-1
Lipid C2 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNPs) for mRNA delivery in vivo. LNPs containing lipid C2 and encapsulating an mRNA reporter selectively accumulate in the liver and spleen but not the heart, lungs, or kidneys in mice. LNPs containing lipid C2 and...
| Keywords: | N1,N4-bis[2-[bis(2-hydroxytetradecyl)amino]ethyl]-1,4-piperazinedipropanamide |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 3003022-09-8 |
| MW: | 1163.9 D |
From 90.00€
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Juglanin
Item number: Cay39824-1
Juglanin is a flavonol that has been found in J. mandshurica and has diverse biological activities. It reduces the levels of reactive oxygen species (ROS) increased by oscillatory shear stress (OSS) in human aortic endothelial cells (HAECs) when used at concentrations of 2.5 and 5 µM. It also reduces OSS-induced...
| Keywords: | Kaempferol-3-O-arabinofuranose, 3-(alpha-L-arabinofuranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| Application: | Bioactive flavonol |
| CAS | 5041-67-8 |
| MW: | 418.4 D |
From 85.00€
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12-oxo Stearic Acid
Item number: Cay40259-100
12-oxo Stearic acid is a saturated oxo fatty acid (SOFA) and metabolite of ricinoleic acid (Cay-10009369) that has been found in cow and goat milk. Dietary administration of 12-oxo stearic acid (0.25%) induces encephalomalacia in chicks fed a vitamin E-deficient diet.Formal Name: 12-oxo-octadecanoic acid. CAS...
| Keywords: | 12-keto Octadecanoic Acid, 12-keto Stearic Acid, 12-oxo C18:0, 12-oxo Octadecanoic Acid, NSC 2103, 12-oxo-octadecanoic acid |
| Application: | Ricinoleic acid metabolite, saturated oxo fatty acid (SOFA) |
| CAS | 925-44-0 |
| MW: | 298.5 D |
From 136.00€
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1-A-N
Item number: Cay40500-1
1-A-N is an ionizable cationic lipid (pKa = 6.8) that has been used in the generation of lipid nanoparticles (LNPs) for siRNA delivery in vivo. LNPs containing 1-A-N and encapsulating siRNA targeting the gene encoding CD45 reduce its gene expression in splenic T cells in mice.Formal Name:...
| Keywords: | 3-(2-((3r,5r,7r)-adamantan-1-yl)acetoxy)-2-((((3-(pyrrolidin-1-yl)propoxy)carbonyl)oxy)methyl)propyl... |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 698 D |
From 62.00€
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Ganglioside GD1b . disodium salt (bovine brain)
Item number: AG-CN2-9004-M001
Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell...
| Keywords: | GD1b . 2Na, Disialoganglioside GD1b . 2Na |
| Application: | Acidic glycosphingolipid |
| CAS | 19553-76-5 |
| MW: | 1836,1 D |
182.00€
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1-Oleoyl-2-acetyl-sn-glycerol
Item number: Cay62600-10
OAG is a cell-permeable analog of the PKC-activating second messenger DAG. It activates PKC in platelets, resulting in the phosphorylation of a 40 kDa protein. OAG is metabolized to its corresponding phosphatidic acid (1-oleoyl-2-acetyl-3-phosphoglycerol), most likely through the action of a diglycerol kinase.Formal...
| Keywords: | OAG, 1-O-9Z-octadecenoyl-2-O-acetyl-sn-glycerol |
| Application: | Bioactive lipid assays |
| CAS | 86390-77-4 |
| MW: | 398.6 D |
From 78.00€
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