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Thielavin A
Item number: Cay21767-2.5
Thielavin A is a fungal metabolite originally isolated from T. terricola that is related to thielavin B (Cay-18770). Thielavin A inhibits COX, blocking both the conversion of arachidonic acid (Cay-90010) to prostaglandin H2 (PGH2, Cay-17020) and the conversion of PGH2 to PGE2 (Cay-14010, IC50s = 10 and 40 µM,...
| Keywords: | 4-[(2,4-dihydroxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,5,6-trimethyl-benzoic acid,... |
| Application: | Fungal metabolite, COX inhibitor |
| CAS | 71950-66-8 |
| MW: | 538.5 D |
From 390.00€
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10(S)-HOME
Item number: Cay33246-1
10(S)-HOME is an oxylipin. It is an intermediate in the conversion of oleic acid (Cay-90260, Cay-24659) to the antibacterial hydroxy fatty acid 7,10-dihydroxy-8(E)-octadecenoic acid (Cay-33447) in P. aeruginosa.Formal Name: 10S-hydroxy-8E-octadecenoic acid. CAS Number: 263023-34-3. Synonyms: HOD. Molecular Formula:...
| Keywords: | HOD, 10S-hydroxy-8E-octadecenoic acid |
| Application: | Oxylipin |
| CAS | 263023-34-3 |
| MW: | 298.5 D |
From 67.00€
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ATX-100
Item number: Cay36935-1
ATX-100 is an ionizable cationic lipid (pKa = 6.38). It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA. Intravenous administration of LNPs containing ATX-100 and encapsulating Factor VII siRNA decrease Factor VII blood levels in mice.Formal Name:...
| Keywords: | 4,4'-[[[[3-(dimethylamino)propyl]thio]carbonyl]imino]bis-butanoic acid, 1,1'-bis(1-heptyloctyl) ester |
| Application: | Cationic ionizable lipid |
| CAS | 2230647-37-5 |
| MW: | 755.2 D |
From 62.00€
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Lipid C24
Item number: Cay37122-1
Lipid C24 is a cationic ionizable lipid. It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs).Formal Name: bis(2-octyldodecyl) 3,3'-((4-(4-methylpiperazin-1-yl)butyl)azanediyl)dipropionate. CAS Number: 2767561-52-2. Molecular Formula: C55H109N3O4. Formula Weight: 876.5....
| Keywords: | bis(2-octyldodecyl) 3,3'-((4-(4-methylpiperazin-1-yl)butyl)azanediyl)dipropionate |
| Application: | Cationic ionizable lipid, LNP formation |
| CAS | 2767561-52-2 |
| MW: | 876.5 D |
From 54.00€
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FTT5
Item number: Cay37413-1
FTT5 is a lipid-like compound that has been used in the formation of lipid-like nanoparticles (LLNs) and is a derivative of the ionizable cationic amino lipid TT3 (Cay-37909). LLNs containing FTT5 and encapsulating an mRNA reporter increase luminescence in Hep3B cells and selectively accumulate in mouse liver. LLNs...
| Keywords: | Functionalized N1,N3,N5-tris(2-aminoethyl)benzene-1,3,5-Tricarboxamide 5,... |
| Application: | Lipid-like compound, LLN formation |
| CAS | 2803606-43-9 |
| MW: | 1989.1 D |
From 90.00€
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OF-02
Item number: Cay37652-1
OF-02 is an ionizable cationic amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA. LNPs containing OF-02 localize to the liver after intravenous administration in mice. Intravenous administration of LNPs containing OF-02 and...
| Keywords: | 3,6-bis[4-[bis[(9Z,12Z)-2-hydroxy-9,12-octadecadien-1-yl]amino]butyl]-2,5-piperazinedione |
| Application: | Ionizable cationic amino lipid, LNP formation |
| CAS | 1883431-67-1 |
| MW: | 1314.1 D |
From 103.00€
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TT3
Item number: Cay37909-1
TT3 is an ionizable cationic amino lipid that has been used in combination with other lipids in the formation of lipid-like nanoparticles (LLNs). Administration of LLNs containing TT3 and encapsulating mRNA encoding human coagulation Factor IX induces human coagulation Factor IX expression in the plasma of...
| Keywords: | N1,N3,N5-tris[3-(didodecylamino)propyl]-1,3,5-benzenetricarboxamide |
| Application: | Ionizable cationic amino lipid, LLN formation |
| CAS | 1821214-50-9 |
| MW: | 1388.4 D |
From 62.00€
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306-N16B
Item number: Cay37927-1
306-N16B is an ionizable cationic lipid. It has been used in the generation of lipid nanoparticles (LNPs). Intravenous administration of LNPs containing 306-N16B and encapsulating an mRNA reporter accumulate specifically in the mouse lung primarily in lung endothelial cells. LNPs containing both 306-N16B and...
| Keywords: | 3,3',3'',3'''-(((methylazanediyl)bis(propane-3,1-diyl))bis(azanetriyl))tetrakis(N-(2-(dodecyldisulfaneyl)ethyl)propanamide) |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 2803699-70-7 |
| MW: | 1471.6 D |
From 48.00€
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Lipid OA2 (hydrochloride)
Item number: Cay37987-10
Lipid OA2 is an ionizable cationic lipid that has been used in the generation of single-component lipid nanoparticles (LNPs) for the delivery of siRNA. LNPs containing lipid OA2 and siRNA targeting the gene encoding suppressor of cytokine signaling 1 (Socs1) decrease Socs1 expression by approximately 50% in isolated...
| Keywords: | KE-oleyl, di((Z)-octadec-9-en-1-yl) L-lysyl-L-glutamate, dihydrochloride |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 849.1 D |
From 103.00€
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OC2-K3-E10
Item number: Cay38243-1
OC2-K3-E10 is an ionizable cationic lipid (pKa = 6.8). It has been used in the formation of lipid nanoparticles (LNPs) for the delivery of CRISPR complementary single-guide RNA (sgRNA) and Cas9 mRNA for genome editing in transgenic mice.Formal Name:...
| Keywords: | I-28, 3,3'-((2-hydroxyethyl)azanediyl)bis(N-(3-(bis(2-hydroxydecyl)amino)propyl)propanamide) |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 942.5 D |
From 103.00€
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Lipid CL1
Item number: Cay38320-10
Lipid CL1 is an ionizable cationic trialkyl lipid that has been used in the formation of lipid nanoparticles (LNPs). LNPs containing lipid CL1 and encapsulating mRNA encoding human erythropoietin (EPO) increase blood EPO protein levels in mice.Formal Name: 5-(dimethylamino)-pentanoic acid,...
| Keywords: | 5-(dimethylamino)-pentanoic acid, (6Z)-1,2-di-(4Z)-4-decen-1-yl-6-dodecen-1-yl ester |
| Application: | Ionizable cationic trialkyl lipid, LNP formation |
| CAS | 1450888-71-7 |
| MW: | 588 D |
From 239.00€
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C13-112-tri-tail
Item number: Cay38383-1
C13-112-tri-trail is an ionizable cationic lipid.Formal Name: 14-(2-hydroxytridecyl)-17,20-dioxa-14,23-diazahexatriacontane-12,25-diol. CAS Number: 1381861-96-6. Molecular Formula: C45H94N2O5. Formula Weight: 743.2. Purity: >90%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMSO:...
| Keywords: | 14-(2-hydroxytridecyl)-17,20-dioxa-14,23-diazahexatriacontane-12,25-diol |
| Application: | Ionizable cationic lipid |
| CAS | 1381861-96-6 |
| MW: | 743.2 D |
From 35.00€
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