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13(S)-HODE
Item number: Cay38610-100
13(S)-HODE is produced by incubation of linoleic acid with plant and mammalian lipoxygenases. It has been shown to inhibit the adhesion of tumor cells to the endothelium at concentrations around 1 µM, and down regulates the expression of the IRGpIIb/IIIa receptor.Formal Name: 13S-hydroxy-9Z,11E-octadecadienoic acid....
| Keywords: | 13S-hydroxy-9Z,11E-octadecadienoic acid |
| Application: | Adhesion inhibitor |
| CAS | 29623-28-7 |
| MW: | 296.5 D |
From 82.00€
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8-iso Prostaglandin F2alpha-d4
Item number: Cay316350-25
8-iso PGF2alpha-d4 is intended for use as an internal standard for the quantification of 8-iso PGF2alpha by GC- or LC-mass spectrometry. 8-iso Prostaglandin F2alpha (8-iso PGF2alpha) is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. It circulates in human...
| Keywords: | 15-F2t-Isoprostane-d4, 8-epi PGF2alpha-d4, 8-Isoprostane-d4, iPF2alpha-III-d4,... |
| Application: | Standard |
| CAS | 211105-40-7 |
| MW: | 358.5 D |
From 226.00€
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5(S)-HpETE
Item number: Cay44230-25
5(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 5-LO on arachidonic acid. It is metabolized to leukotriene A4 (LTA4), a key intermediate in the formation of LTs. 5(S)-HpETE (1 µM) mediates the induction of the proto-oncogene c-fos in TNF-stimulated TA1 cells.Formal Name:...
| Keywords: | 5S-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 71774-08-8 |
| MW: | 336.5 D |
From 146.00€
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(±)11(12)-DiHET
Item number: Cay51511-25
Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. (±)11(12)-DiHET relaxes U-46619 (Cay-16450)-contracted artery rings with approximately 70% of the magnitude of (±)11(12)-EET (Cay-50511).Formal Name: (±)11,12-dihydroxy-5Z,8Z,14Z-eicosatrienoic...
| Keywords: | (±)11,12-DiHETrE, (±)11,12-dihydroxy-5Z,8Z,14Z-eicosatrienoic acid |
| Application: | Bioactive lipid studies |
| MW: | 338.5 D |
From 133.00€
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gamma-Linolenic Acid
Item number: Cay90220-50
gamma-Linolenic acid (GLA) is an omega-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak LTB4 receptor antagonist, inhibiting [3H]-LTB4 binding to porcine neutrophil membranes with a Ki of 1 µM. GLA produces 53% inhibition at a 1 mg/kg dose in an in vivo model...
| Keywords: | GLA, 6Z,9Z,12Z-octadecatrienoic acid |
| Application: | LTB4 receptor antagonist |
| CAS | 506-26-3 |
| MW: | 278.4 D |
From 35.00€
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Arachidonic Acid (sodium salt)
Item number: Cay10006607-100
Polyunsaturated fatty acids (PUFAs) are essential nutrients that show distinct deficiency syndromes when not present in adequate amounts in the diet. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free...
| Keywords: | Sodium Arachidonate, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, monosodium salt |
| Application: | Bioactive lipid assays |
| CAS | 6610-25-9 |
| MW: | 326.5 D |
From 69.00€
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Docosahexaenoic Acid-d5
Item number: Cay10005057-50
Docosahexaenoic acid-d5 (DHA-d5) is intended for use as an internal standard for the quantification of DHA (Cay-90310) by GC- or LC-MS. DHA is a long-chain omega-3 polyunsaturated fatty acid (PUFA) found in fish and algal oils. It comprises approximately 40% of total brain PUFAs and is abundant in grey matter and...
| Keywords: | Cervonic Acid-d5, DHA-d5, 4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic-21,21,22,22,22-d5 acid |
| Application: | Standard |
| CAS | 1197205-71-2 |
| MW: | 333.5 D |
From 94.00€
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Docosahexaenoyl Ethanolamide
Item number: Cay10007534-5
Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant omega-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for...
| Keywords: | DEA, DHEA, Synaptamide, N-(2-hydroxyethyl)-4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenamide |
| Application: | Bioactive lipid assays |
| CAS | 162758-94-3 |
| MW: | 371.6 D |
From 48.00€
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1-Oleoyl-2-hydroxy-sn-glycero-3-PA
Item number: Cay10010093-5
1-Oleoyl-2-hydroxy-sn-glycero-3-PA (1-Oleoyl LPA) is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by...
| Keywords: | 1-Oleoyl LPA, Oleoyl-sn-3-Glycerophosphate, 1-O-9Z-octadecenoyl-sn-glyceryl-3-phosphoric acid |
| Application: | Bioactive lipid assays |
| CAS | 65528-98-5 |
| MW: | 436.5 D |
From 36.00€
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C16 Ceramide (d18:1/16:0)
Item number: Cay10681-1
C16 Ceramide is a sphingolipid. It incorporates into the mitochondrial outer membrane and forms channels that increase its permeability. C16 Ceramide levels are increased by PPMP or MAPP in isolated human neutrophils and are correlated with an increase in apoptosis. It accumulates in the lungs of patients with...
| Keywords: | Cer(d18:1/16:0), Ceramide (d18:1/16:0), N-Palmitoyl-D-erythro-Sphingosine, Palmitoyl Ceramide,... |
| Application: | Bioactive lipid assays |
| CAS | 24696-26-2 |
| MW: | 537.9 D |
From 31.00€
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(±)5(6)-DiHET
Item number: Cay51211-25
5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET (Cay-50211, Cay-10007260) by epoxide hydrolases. 5(6)-DiHET can be used to quantify 5(6)-EET due to the conversion of 5(6)-EET to 5(6)-delta-lactone in solution. 5(6)-DiHET activates large-conductance calcium-activated...
| Keywords: | (±)5,6-DiHETrE, (±)5,6-dihydroxy-8Z,11Z,14Z-eicosatrienoic acid |
| Application: | Bioactive lipid assays |
| CAS | 213382-49-1 |
| MW: | 338.5 D |
From 126.00€
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PPZ-A10
Item number: Cay9004144-5
PPZ-A10 is an ionizable cationic lipid. It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA in vitro and in vivo. Intraperitoneal administration of LNPs containing PPZ-A10 and encapsulating an mRNA reporter preferentially accumulates in hepatic Kupffer cells and...
| Keywords: | N,N'-(piperazine-1,4-diylbis(propane-3,1-diyl))bis(3-(didecylamino)propanamide) |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 903.6 D |
From 130.00€
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