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C12 NBD dihydro Ceramide (d18:0/12:0)
Item number: Cay10008097-1
Ceramidase catalyzes the hydrolysis of the N-acyl linkage between the fatty acid and sphingosine base in ceramide to produce sphingosine and a free fatty acid. Three isoforms of ceramidases (acid, neutral, and alkaline) have been characterized based on differences in their catalytic pH optimum. C12 NBD dihydro...
| Keywords: | NBD Cer(d18:0/12:0), NBD Ceramide (d18:0/12:0),... |
| Application: | Bioactive lipid assays |
| CAS | 474943-05-0 |
| MW: | 661.9 D |
From 136.00€
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DMPE-MPEG(2000)
Item number: Cay34649-100
DMPE-MPEG(2000) is a PEGylated derivative of 1,2-dimyristoyl-rac-glycero-3-PE (DMPE). It has been used in the synthesis of nanostructured lipid carriers (NLCs) for use in ocular administration of ciprofloxacin (Cay-14286).Formal Name:...
| Keywords: | 1,2-Dimyristoyl-rac-glycero-3-PE-methoxy-Polyethyleneglycol-2000, 1,2-DMPE-MPEG(2000),... |
| Application: | DMPE PEGylated form |
| CAS | 1254157-61-3 |
From 126.00€
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RM 137-15
Item number: Cay38918-1
RM 137-15 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo. LNPs containing RM 137-15 and encapsulating mRNA encoding a fluorescent reporter increase fluorescence in the livers of mice.Formal Name:...
| Keywords: | (9Z,9'Z)-((3,3'-((2-(4-methylpiperazin-1-yl)ethyl)azanediyl)bis(propanoyl))bis(oxy))bis(octadec-9-ene-18,7-diyl)... |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 1441.3 D |
From 99.00€
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C23 Phytoceramide (t18:0/23:0)
Item number: Cay9004471-1
C23 Phytoceramide (t18:0/23:0) is a long-chain sphingolipid that has been found in C. sinensis.Formal Name: N-[2S,3R-dihydroxy-1S-(hydroxymethyl)heptadecyl]-tricosanamide. CAS Number: 844866-89-3. Synonyms: C23 Phytosphingosine (t18:0/23:0), Ceramide (t18:0/23:0), Cer(t18:0/23:0), N-Tricosanoyl Phytosphingosine....
| Keywords: | C23 Phytosphingosine (t18:0/23:0), Cer(t18:0/23:0), Ceramide (t18:0/23:0), N-Tricosanoyl Phytosphingosine,... |
| Application: | Long-chain sphingolipid |
| CAS | 844866-89-3 |
| MW: | 654.1 D |
From 37.00€
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Xestospongin C
Item number: Cay64950-10
Xestospongin C is a marine natural product which was first isolated from Pacific basin sponges, and noted to have vasodilatory properties. Xestospongin C antagonizes the calcium-releasing action of inositol-1,4,5-trisphosphate (IP3) at the receptor level. Inositol phosphates are important signal transduction...
| Keywords: | Araguspongine E, XeC,... |
| Application: | Bioactive lipid assays |
| CAS | 88903-69-9 |
| MW: | 446.7 D |
From 117.00€
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Prostaglandin J2
Item number: Cay18500-500
Prostaglandin J2 (PGJ2) is a metabolite of PGD2 (Cay-12010) and an agonist of the prostaglandin D2 (PGD2) receptor subtypes DP1 and DP2/CRTH. It is formed from PGD2 by spontaneous dehydration. PGJ2 binds to DP1 and DP2/CRTH receptors (Kis = 0.9 and 6.6 nM, respectively) and either increases or inhibits the...
| Keywords: | PGJ2, 11-oxo-15S-hydroxy-prosta-5Z,9,13E-trien-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 60203-57-8 |
| MW: | 334.5 D |
From 121.00€
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CL4H6
Item number: Cay37279-10
CL4H6 is an ionizable cationic amino lipid (apparent pKa = 6.35) that has been used in the generation of lipid nanoparticles (LNPs). LNPs containing CL4H6 and encapsulating Factor VII-targeting siRNA decrease hepatic levels of Factor VII in mice. Intravenous administration of LNPs containing CL4H6 and encapsulating...
| Keywords: | 9-octadecenoic acid, 1,1'-[7-[4-(dipropylamino)butyl]-7-hydroxy-1,13-tridecanediyl] ester |
| Application: | Ionizable amino lipid, LNP formation |
| CAS | 2256087-35-9 |
| MW: | 916.5 D |
From 103.00€
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8-iso Prostaglandin E1
Item number: Cay13360-10
Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin. 8-iso Prostaglandin E1 (8-iso PGE1) is an isoprostane which is found in human semen at levels of 7 µg/ml. It is a pulmonary vasoconstrictor in anesthetized dogs with a potency similar to PGF2alpha.Formal Name:...
| Keywords: | 8-epi PGE1, 8-iso PGE1, Ovinonic acid, 9-oxo-11alpha,15S-dihydroxy-(8beta)-prost-13E-en-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 21003-46-3 |
| MW: | 354.5 D |
From 70.00€
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tetranor-PGEM
Item number: Cay14840-25
tetranor-Prostaglandin E metabolite (tetranor-PGEM) is the major urinary metabolite of PGE2 (Cay-14010). Urine levels of tetranor-PGEM are increased in patients with diabetic nephropathy. Increased urine levels are also associated with a higher risk of breast cancer in postmenopausal women with a body mass index...
| Keywords: | tetranor-Prostaglandin E Metabolite, 9,15-dioxo-11alpha-hydroxy-13,14-dihydro-2,3,4,5-tetranor-prostan-1,20-dioic acid |
| Application: | Bioactive lipid assays |
| CAS | 24769-56-0 |
| MW: | 328.4 D |
From 182.00€
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N-Arachidonoyl Dopamine
Item number: Cay90057-5
N-Arachidonoyl dopamine (NADA) is an arachidonoyl amino acid and cannabinoid (CB) receptor 1 agonist (Ki = 250 nM in rat brain membranes, which highly express CB1 receptors). It is selective for CB1 over CB2 receptors (Ki = 12,000 nM in rat spleen membranes, which highly express CB2 receptors). NADA induces...
| Keywords: | NADA, N-[2-(3,4-dihydroxyphenyl)ethyl]-5Z,8Z,11Z,14Z-eicosatetraenamide |
| Application: | CB1 agonist |
| CAS | 199875-69-9 |
| MW: | 439.6 D |
From 74.00€
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17-Octadecynoic Acid
Item number: Cay90270-1
17-Octadecynoic Acid (17-ODYA) is a fatty acid alkyne. It is a suicide inhibitor of leukotriene B4 20-hydroxylase and renal CYP450 omega-hydroxylase. 17-ODYA (10 µM) completely inhibits the bradykinin-dependent transport of sodium chloride in rat TALH cells. It has been used as a click chemistry probe for labeling...
| Keywords: | 17-ODYA, Alk-16 |
| Application: | Bioactive lipid assays |
| CAS | 34450-18-5 |
| MW: | 280.5 D |
From 23.00€
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Tauroursodeoxycholic Acid
Item number: Cay20277-500
Tauroursodeoxycholic acid (TUDCA) is a taurine-conjugated form of the secondary bile acid ursodeoxycholic acid (Cay-15121). TUDCA is found in small quantities in human bile but at a higher concentration in the bile of black bears. It demonstrates anti-apoptotic activity in rodent models of tauopathy, Huntington's...
| Keywords: | 3alpha,7beta-dihydroxy-5beta-cholanoyl Taurine, TUDCA, UR-906,... |
| Application: | Secondary bile acid taurine conjugate |
| CAS | 14605-22-2 |
| MW: | 499.7 D |
From 78.00€
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