9,10-Dihydroxystearic Acid

9,10-Dihydroxystearic acid is an oxidation product of oleic acid (Cay-90260, Cay-24659) that can be formed from oleic acid in HepG2 cells. It activates peroxisome proliferator-activated receptor alpha (PPARalpha) in CV-1 cells when used at concentrations ranging from 50 to 100 µM. 9,10-Dihydroxystearic acid (4% in the diet) decreases blood glucose levels, increases insulin sensitivity, and decreases body weight in high-fat diet-fed KKAy diabetic mice.Formal Name: 9,10-dihydroxy-octadecanoic acid. CAS Number: 120-87-6. Synonyms: NSC 60305. Molecular Formula: C18H36O4. Formula Weight: 316.5. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25mg/mL, DMSO: 10mg/mL, DMSO:PBS (pH 7.2) (1:5): 0.16mg/mL, Ethanol: 5mg/mL. SMILES: OC(CCCCCCCC(O)C(O)CCCCCCCC)=O. InChi Code: InChI=1S/C18H36O4/c1-2-3-4-5-7-10-13-16(19)17(20)14-11-8-6-9-12-15-18(21)22/h16-17,19-20H,2-15H2,1H3,(H,21,22). InChi Key: VACHUYIREGFMSP-UHFFFAOYSA-N.