(±)5(6)-EET methyl ester

(±)5(6)-EET (Cay-50211) is biosynthesized in rat and rabbit liver microsomes by CYP450. In neuroendocrine cells, such as the anterior pituitary and pancreatic islet, (±)5(6)-EET has been implicated in the mobilization of Ca2+ and hormone secretion. Since (±)5(6)-EET is highly unstable, (±)5(6)-EET methyl ester is used for bulk storage and small amounts converted to the free acid just before use.Formal Name: (±)5,6-epoxy-8Z,11Z,14Z-eicosatrienoic acid, methyl ester. Synonyms: (±)5,6-EpETrE methyl ester. Molecular Formula: C21H34O3. Formula Weight: 334.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS pH 7.2: 1 mg/ml. SMILES: CCCCC/C=C\C/C=C\C/C=C\C[C@@H](O1)[C@@H]1CCCC(OC)=O. InChi Code: InChI=1S/C21H34O3/c1-3-4-5-6-7-8-9-10-11-12-13-14-16-19-20(24-19)17-15-18-21(22)23-2/h7-8,10-11,13-14,19-20H,3-6,9,12,15-18H2,1-2H3/b8-7-,11-10-,14-13-/t19-,20+/m1/s1. InChi Key: XGESKIWNDBIILZ-IPMPHHSQSA-N.