4-hydroxy Nonenal Mercapturic Acid

4-hydroxy Nonenal Mercapturic Acid
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay32110-1 1 mg -

6 - 10 business days*

110.00€
Cay32110-5 5 mg -

6 - 10 business days*

465.00€
Cay32110-10 10 mg -

6 - 10 business days*

819.00€
 
Peroxidation of common omega-6 polyunsaturated fatty acids (PUFAs) such as linoleic acid, DGLA,... more
Product information "4-hydroxy Nonenal Mercapturic Acid"
Peroxidation of common omega-6 polyunsaturated fatty acids (PUFAs) such as linoleic acid, DGLA, and arachidonic acid can give rise to 4-HNE. 4-HNE is cleared rapidly from the plasma and undergoes enterohepatic circulation as a glutathione conjugate in the rat. About two thirds of an administered dose of 4-HNE is excreted within 48 hours in the urine, primarily in the form of mercapturic acid conjugates. The C-1 aldehyde of 4-HNE is reduced to an alcohol in about half of these metabolites. The remainder are C-1 aldehydes or have been oxidized to C-1 carboxylic acids. These aldehydes and carboxylic acids can also form gamma-lactols and gamma-lactones, respectively, producing at least 4 or 5 end urinary metabolites of 4-HNE in vivo.Formal Name: N-acetyl-S-(tetrahydro-5-hydroxy-2-pentyl-3-furanyl)-L-cysteine. CAS Number: 146764-24-1. Molecular Formula: C14H25NO5S. Formula Weight: 319.4. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS pH 7.2: 0.1 mg/ml. SMILES: CCCCCC1OC(O)CC1SC[C@H](NC(=O)C)C(=O)O. InChi Code: InChI=1S/C14H25NO5S/c1-3-4-5-6-11-12(7-13(17)20-11)21-8-10(14(18)19)15-9(2)16/h10-13,17H,3-8H2,1-2H3,(H,15,16)(H,18,19). InChi Key: DEWNQQSQBYUUAE-UHFFFAOYSA-N.
Keywords: N-acetyl-S-(tetrahydro-5-hydroxy-2-pentyl-3-furanyl)-L-cysteine
Supplier: Cayman Chemical
Supplier-Nr: 32110

Properties

Application: Bioactive lipid assays
MW: 319.4 D
Formula: C14H25NO5S
Purity: >98%
Format: Solution

Database Information

CAS : 146764-24-1| Matching products

Handling & Safety

Storage: -80°C
Shipping: -80°C (International: -80°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H319
P Phrases: P210, P233, P240, P241, P242, P243, P264, P280, P303+P361+P353, P305+P351+P338, P337+P313, P370+P378, P403+P235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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