4-Hexylresorcinol

4-Hexylresorcinol is an alkylresorcinol that has been found in rye. 4-Hexylresorcinol-containing lozenges are active against S. aureus, S. pyogenes, M. catarrhalis, H. influenzae, and F. necrophorum in an in vitro model of oral transmucosal delivery. It increases the activities of glutathione peroxidase (GPX), glutathione reductase (GR), and catalase in isolated human peripheral blood lymphocytes when used at concentrations of 25, 50, or 100 µM. 4-Hexylresorcinol (2.5 mg/kg) in combination with cisplatin (Cay-13119) reduces tumor growth and increases survival in a patient-derived xenograft (PDX) mouse model of oral mucosal melanoma. Formulations containing 4-hexylresorcinol have been used as food additives to prevent browning in produce and shrimp.Formal Name: 4-hexyl-1,3-benzenediol. CAS Number: 136-77-6. Synonyms: 4-n-Hexylresorcinol, NSC 1570, p-Hexylresorcinol. Molecular Formula: C12H18O2. Formula Weight: 194.3. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2) (1:4): 0.20 mg/ml, PBS (pH 7.2): Slightly soluble. SMILES: OC1=CC(O)=C(CCCCCC)C=C1. InChi Code: InChI=1S/C12H18O2/c1-2-3-4-5-6-10-7-8-11(13)9-12(10)14/h7-9,13-14H,2-6H2,1H3. InChi Key: WFJIVOKAWHGMBH-UHFFFAOYSA-N. Origin: Synthetic.