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You can also order by e-mail: info@biomol.com
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You can also order by e-mail: info@biomol.com
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C-12 NBD cholesterol is a fluorescently tagged cholesterol with the hydrophilic NBD fluorophore... more
Product information "3-dodecanoyl-NBD Cholesterol"
C-12 NBD cholesterol is a fluorescently tagged cholesterol with the hydrophilic NBD fluorophore attached to the hydrophilic end of cholesterol, separated by a 12-carbon spacer. This design allows the cholesterol to properly orient in membrane bilayers while the fluorescent tag is presented outside of the bilayer. This should model the behavior of cholesterol in membranes better than the previously used 25-NBD cholesterol, which positions NBD directly on the 25th carbon of cholesterol at the hydrophobic terminus. NBD has excitation/emission maxima of 465/535 nm, respectively. Fluorescently tagged lipids have been used to study their interactions with proteins, their utilization by cells and liposomes, and for the development of assays for lipid metabolism.Formal Name: 12-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-(3S,10R,13R)-3-methoxy-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-tetradecahydro-1H-cyclopenta[alpha]phenanthrene. CAS Number: 1246303-05-8. Synonyms: 3-C12-NBD Cholesterol. Molecular Formula: C45H70N4O5. Formula Weight: 747.1. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 1 mg/ml, DMSO: 0.25 mg/ml, Ethanol: 1 mg/ml. lambdamax: 229, 335, 465 nm. SMILES: [H]N(C1=CC=C([N+]([O-])=O)C2=NON=C12)CCCCCCCCCCCCC(O[C@H](C3)CC[C@@]4(C)C3=CC[C@]5([H])[C@]4([H])CC[C@@]6(C)[C@@]5([H])CC[C@]6([H])[C@@](C)([H])CCCC(C)C)=O. InChi Code: InChI=1S/C45H70N4O5/c1-31(2)16-15-17-32(3)36-21-22-37-35-20-19-33-30-34(25-27-44(33,4)38(35)26-28-45(36,37)5)53-41(50)18-13-11-9-7-6-8-10-12-14-29-46-39-23-24-40(49(51)52)43-42(39)47-54-48-43/h19,23-24,31-32,34-38,46H,6-18,20-22,25-30H2,1-5H3/t32-,34. InChi Key: TXCIESALPKGCNM-QNKNOTAZSA-N.
Keywords: | 3-C12-NBD Cholesterol, 12-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-(3S,10R,13R)-3-methoxy-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-tetradecahydro-1H-cyclopenta[alpha]phenanthrene |
Supplier: | Cayman Chemical |
Supplier-Nr: | 13220 |
Properties
Application: | Bioactive lipid assays |
MW: | 747.1 D |
Formula: | C45H70N4O5 |
Purity: | >98% |
Format: | Solution |
Database Information
CAS : | 1246303-05-8| Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
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H Phrases: | H225, H319, H333 |
P Phrases: | P210, P233, P240, P241, P242, P243, P264, P280, P304, P312, P303+P361+P353, P305+P351+P338, P337+P313, P370+P378, P403+P235, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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