244cis

244cis
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay39284-5 5 mg -

6 - 10 business days*

125.00€
Cay39284-10 10 mg -

6 - 10 business days*

225.00€
Cay39284-25 25 mg -

6 - 10 business days*

404.00€
 
244cis is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles... more
Product information "244cis"
244cis is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs). LNPs containing 244cis and encapsulating an mRNA reporter specifically accumulate in the lungs and induce lower serum chemokine (C-C motif) ligand 2 (CCL2) levels than LNPs containing SM-102 (Cay-33474) in mice. Intravenous administration of LNPs containing 244cis and encapsulating mRNA encoding Cre recombinase increases tdTomato fluorescence in lung endothelial, epithelial, and immune cells, as well as fibroblasts, in mice expressing a floxed STOP codon to prevent tdTomato expression.Formal Name: 4-[2-[bis[9-[(2Z)-2-nonen-1-yloxy]-9-oxononyl]amino]ethyl]-1-piperazinenonanoic acid, (2Z)-2-nonen-1-yl ester. CAS Number: 2956402-64-3. Molecular Formula: C60H111N3O6. Formula Weight: 970.6. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Ethanol: 25 mg/ml. SMILES: O=C(OC/C=C\CCCCCC)CCCCCCCCN1CCN(CCN(CCCCCCCCC(OC/C=C\CCCCCC)=O)CCCCCCCCC(OC/C=C\CCCCCC)=O)CC1. InChi Code: InChI=1S/C60H111N3O6/c1-4-7-10-13-22-31-40-55-67-58(64)43-34-25-16-19-28-37-46-61(47-38-29-20-17-26-35-44-59(65)68-56-41-32-23-14-11-8-5-2)49-52-63-53-50-62(51-54-63)48-39-30-21-18-27-36-45-60(66)69-57-42-33-24-15-12-9-6-3/h31-33,40-42H,4-30,34-39,43-57H2,1-3H3/b40-31-,41-32-,42-33-. InChi Key: LLTJKESWTCPZGG-IHTYGJSSSA-N.
Keywords: di((Z)-non-2-en-1-yl) 9,9'-((2-(4-(9-(((Z)-non-2-en-1-yl)oxy)-9-oxononyl)piperazin-1-yl)ethyl)azanediyl)dinonanoate
Supplier: Cayman Chemical
Supplier-Nr: 39284

Properties

Application: Ionizable cationic lipid, LNP formation
MW: 970.6 D
Formula: C60H111N3O6
Purity: >95%
Format: Solution

Database Information

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H319, H333
P Phrases: P210, P233, P240, P241, P242, P243, P264, P280, P304, P312, P303+P361+P353, P305+P351+P338, P337+P313, P370+P378, P403+P235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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