15-OxoEDE

15-OxoEDE is produced by the oxidation of 15-HEDE. 15-OxoEDE inhibits 5-LO from RBL-1 cells with an IC50 of 55 µM, which is about 2-fold lower than 15(S)-HEDE. A related oxo-eicosanoid, 5-oxoETE, is biosynthesized from 5(S)-HETE by a specific dehydrogenase and has potent inflammatory activity.Formal Name: 15-oxo-11Z,13E-eicosadienoic acid. CAS Number: 105835-44-7. Synonyms: 15-KEDE. Molecular Formula: C20H34O3. Formula Weight: 322.5. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS pH 7.2: 1 mg/ml. lambdamax: 279 nm. SMILES: CCCCCC(=O)/C=C\C=C\CCCCCCCCCC(=O)O. InChi Code: InChI=1S/C20H34O3/c1-2-3-13-16-19(21)17-14-11-9-7-5-4-6-8-10-12-15-18-20(22)23/h9,11,14,17H,2-8,10,12-13,15-16,18H2,1H3,(H,22,23)/b11-9-,17-14+. InChi Key: QZCMHXPXGACWLJ-QWAPPMFBSA-N.