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15-keto Latanoprost is an active metabolite of the FP receptor agonist latanoprost (Cay-16812). Intraocular administration of 15-keto latanoprost (1 µg/eye) reduces intraocular pressure in cynomolgus monkeys. It also reduces pupillary diameter in cats when administered topically at a dose of 5 µg/eye. 15-keto Latanoprost is a potential pharmaceutical impurity found in commercial preparations of latanoprost.Formal Name: 9alpha,11alpha-dihydroxy-15-oxo-17-phenyl-18,19,20-trinor-prost-5Z-en-1-oic acid, isopropyl ester. CAS Number: 135646-98-9. Molecular Formula: C26H38O5. Formula Weight: 430.6. Purity: >98%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: 100 mg/ml, DMSO: 100 mg/ml, DMSO:PBS (1:12): 80 µg/ml, Ethanol: 100 mg/ml. SMILES: O[C@@H]1[C@H](C/C=C\CCCC(OC(C)C)=O)[C@@H](CCC(CCC2=CC=CC=C2)=O)[C@H](O)C1. InChi Code: InChI=1S/C26H38O5/c1-19(2)31-26(30)13-9-4-3-8-12-22-23(25(29)18-24(22)28)17-16-21(27)15-14-20-10-6-5-7-11-20/h3,5-8,10-11,19,22-25,28-29H,4,9,12-18H2,1-2H3/b8-3-/t22-,23-,24+,25-/m1/s1. InChi Key: DKYCMQSMHPIBBZ-VIZYZFHWSA-N.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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