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Product information "13,14-dihydro-15-keto-tetranor Prostaglandin D2"
A common metabolic pathway for several prostaglandins (PGs), including prostaglandin D2 (PGD2), involves the reduction of the double bond between C-13 and C-14 and oxidation of the hydroxyl group at C-15, producing 13,14-dihydro-15-keto PGs. The removal of four carbons at the alpha-terminus and oxidation of the terminal omega-carbon produces the abundant urinary metabolites, including tetranor-PGDM. 13,14-dihydro-15-keto-tetranor PGD2 is a potential metabolite of PGD2. It would be produced from the known metabolite 13,14-dihydro-15-keto PGD2 (Cay-12610), which is a known agonist for the CRTH2/DP2 receptor.Formal Name: 9alpha-hydroxy-11,15-dioxo-2,3,4,5-tetranor-prostanoic acid. CAS Number: 1204116-69-7. Synonyms: 13,14-dihydro-15-keto-tetranor PGD2. Molecular Formula: C16H26O5. Formula Weight: 298.4. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): 1 mg/ml. SMILES: O[C@@H](C1)[C@H](CCC(O)=O)[C@@H](CCC(CCCCC)=O)C1=O. InChi Code: InChI=1S/C16H26O5/c1-2-3-4-5-11(17)6-7-12-13(8-9-16(20)21)15(19)10-14(12)18/h12-13,15,19H,2-10H2,1H3,(H,20,21)/t12-,13-,15+/m1/s1. InChi Key: CIXGXJHOQWHINC-NFAWXSAZSA-N.
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