12(S)-HETE-19,20-alkyne

12(S)-HETE (Cay-34570) is the predominant lipoxygenase product of mammalian platelets. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM. 12(S)-HETE-19,20-alkyne is a form of 12(S)-HETE with an omega-terminal alkyne. The terminal alkyne group can be used in click chemistry linking reactions, to tag 12(S)-HETE with fluorescent or biotinylated labels for analysis of its metabolism and biological activity.Formal Name: (S,5Z,8Z,10E,14Z)-12-hydroxyicosa-5,8,10,14-tetraen-19-ynoic acid. Synonyms: Click Tag(TM) 12(S)-HETE-19,20-alkyne, 12(S)-Hydroxyeicosatetraenoic Acid-19,20-alkyne. Molecular Formula: C20H28O3. Formula Weight: 316.4. Purity: >97%. Formulation: (Request formulation change), A solution in ethanol. Solubility: 0.1 M Na2CO3: 2 mg/ml, DMF: Miscible, DMSO: Miscible, Ethanol: Miscible, PBS (pH 7.2): 0.5 mg/ml. lambdamax: 236 nm. SMILES: C#CCCC/C=C\C[C@H](O)/C=C/C=C\C/C=C\CCCC(O)=O. InChi Code: InChI=1S/C20H28O3/c1-2-3-4-5-10-13-16-19(21)17-14-11-8-6-7-9-12-15-18-20(22)23/h1,7-11,13-14,17,19,21H,3-6,12,15-16,18H2,(H,22,23)/b9-7-,11-8-,13-10-,17-14+/t19-/m0/s1. InChi Key: YNUPBNFKEDXDHP-LQWMCKPYSA-N.