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![11-cis Retinal](https://www.biomol.com/media/image/d3/16/6a/Cay21377-2_600x600.png)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay21377-2 | 2 mg | - |
6 - 10 business days* |
3,601.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
11-cis Retinal is a chromophore that binds to opsin in the mammalian visual system as an inverse... more
Product information "11-cis Retinal"
11-cis Retinal is a chromophore that binds to opsin in the mammalian visual system as an inverse agonist forming the inactive conformation of rhodopsin. When 11-cis retinal absorbs a photon of light, it isomerizes to form all-trans retinal (Cay-18449) beginning the phototransduction cycle, which is the basis for mammalian vision. A G121L mutation in opsin allows 11-cis retinal to bind as a partial agonist and activate rhodopsin in the absence of light. In a moth model of carotenoid deficiency-induced low visual sensitivity, 11-cis retinal application to compound eyes restored visual sensitivity almost completely.Formal Name: (2E,4Z,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenal. CAS Number: 564-87-4. Synonyms: 11-cis Retinaldehyde, 11-cis Vitamin A aldehyde. Molecular Formula: C20H28O. Formula Weight: 284.4. Purity: >65%. Formulation: (Request formulation change), An oil. Solubility: Chloroform: Slightly Soluble, Methanol: Slightly Soluble. SMILES: CC1=C(/C=C/C(C)=C/C=C\C(C)=C\C([H])=O)C(C)(C)CCC1. InChi Code: InChI=1S/C20H28O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,15H,7,10,14H2,1-5H3/b9-6-,12-11+,16-8+,17-13+. InChi Key: NCYCYZXNIZJOKI-IOUUIBBYSA-N.
Keywords: | 11-cis Retinaldehyde, 11-cis Vitamin A aldehyde, 11-cis-retinal |
Supplier: | Cayman Chemical |
Supplier-Nr: | 21377 |
Properties
Application: | Rhodopsin component |
MW: | 284.4 D |
Formula: | C20H28O |
Purity: | >65% |
Format: | Solution |
Database Information
CAS : | 564-87-4| Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -80°C (International: -80°C) |
Signal Word: | Warning |
GHS Hazard Pictograms: |
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H Phrases: | H302, H315, H361 |
P Phrases: | P201, P202, P264, P270, P280, P321, P330, P301+P310, P302+P352, P308+P313, P332+P313, P362+P364, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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