11-cis Retinal

11-cis Retinal
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay21377-2 2 mg -

6 - 10 business days*

2,811.00€
 
11-cis Retinal is a chromophore that binds to opsin in the mammalian visual system as an inverse... more
Product information "11-cis Retinal"
11-cis Retinal is a chromophore that binds to opsin in the mammalian visual system as an inverse agonist forming the inactive conformation of rhodopsin. When 11-cis retinal absorbs a photon of light, it isomerizes to form all-trans retinal (Cay-18449) beginning the phototransduction cycle, which is the basis for mammalian vision. A G121L mutation in opsin allows 11-cis retinal to bind as a partial agonist and activate rhodopsin in the absence of light. In a moth model of carotenoid deficiency-induced low visual sensitivity, 11-cis retinal application to compound eyes restored visual sensitivity almost completely.Formal Name: (2E,4Z,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenal. CAS Number: 564-87-4. Synonyms: 11-cis Retinaldehyde, 11-cis Vitamin A aldehyde. Molecular Formula: C20H28O. Formula Weight: 284.4. Purity: >65%. Formulation: (Request formulation change), An oil. Solubility: Chloroform: Slightly Soluble, Methanol: Slightly Soluble. SMILES: CC1=C(/C=C/C(C)=C/C=C\C(C)=C\C([H])=O)C(C)(C)CCC1. InChi Code: InChI=1S/C20H28O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,15H,7,10,14H2,1-5H3/b9-6-,12-11+,16-8+,17-13+. InChi Key: NCYCYZXNIZJOKI-IOUUIBBYSA-N.
Keywords: 11-cis Retinaldehyde, 11-cis Vitamin A aldehyde, 11-cis-retinal
Supplier: Cayman Chemical
Supplier-Nr: 21377

Properties

Application: Rhodopsin component
MW: 284.4 D
Formula: C20H28O
Purity: >65%
Format: Solution

Database Information

CAS : 564-87-4| Matching products

Handling & Safety

Storage: -80°C
Shipping: -80°C (International: -80°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H302, H315, H361
P Phrases: P201, P202, P264, P270, P280, P321, P330, P301+P310, P302+P352, P308+P313, P332+P313, P362+P364, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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